Composition, form of production and packaging
? Tablets from brown to dark brown with interspersed, flat, round, with bevelled edges, with the squeezed word "CIPLA" on one side and the fault line on the other.
1 tab.
extract of senna leaves 93.33 mg,
with the content of the sum of calcium salts of sennosides A and B in terms of sennoside B, 13.5 mg
[PRING] lactose 23.07 mg, starch 43.56 mg, methylparahydroxybenzoate 0.04 mg, microcrystalline cellulose 15 mg, talc 11.13 mg, magnesium stearate 0.93 mg, sodium lauryl sulfate 0.93 mg, carmellose sodium 2 mg.
20 pcs. - blisters (2) - packs of cardboard.
20 pcs. - blisters (3) - packs of cardboard.
20 pcs. - blisters (25) - cardboard boxes.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2013.
PHARMACHOLOGIC EFFECT
Laxative means of plant origin. Has a laxative effect, occurring after 8-10 hours. The laxative effect is due to the effect on the receptors of the large intestine, which enhances peristalsis.
PHARMACOKINETICS
In accordance with the International Convention (EMEAHMPWG11 / 99), clinical studies of herbal preparations do not require an isolated study of pharmacokinetic parameters.
INDICATIONS
- constipation caused by hypotension and sluggish peristalsis of the large intestine;
- regulation of stool with hemorrhoids, proctitis, anal fissures.
DOSING MODE
The drug is administered orally, as a rule, 1 time / day in the evening before going to bed, washed down with water or some kind of a drink.
Adults and children over 12 years of age - 1 tab. 1 time / day. If there is no effect, the dose can be increased to 2-3 tablets.
Children aged 6-12 years are prescribed 1/2 tablet. 1 time / day and, if necessary, increase the dose to 1-2 tablets.
In the process of selection, the same dose should be taken for several days and gradually increase it by 1/2 tab. If after reaching the maximum dose within 3 days of defecation does not occur, you need to see a doctor.
SIDE EFFECT
On the part of the digestive system: there may be colic pain in the abdomen, flatulence; with prolonged use, especially in high doses, melanin may be deposited in the intestinal mucosa, nausea, vomiting, diarrhea.
From the side of metabolism: with prolonged use, especially in high doses, there may be disturbances in water-electrolyte metabolism, the deposition of melanin in the intestinal mucosa.
From the side of the urinary system: with prolonged use, especially in high doses, albuminuria, hematuria, and urine discolouration are possible.
From the side of the central nervous system: with prolonged use, especially in high doses, cramps, fatigue, confusion may occur.
Dermatological reactions: with prolonged use, especially in high doses, a skin rash is possible.
From the side of the cardiovascular system: with prolonged use, especially in high doses, a vascular collapse is possible.
CONTRAINDICATIONS
- Spastic constipation;
- intestinal obstruction;
- abdominal pain of unknown origin;
- strangulated hernia;
- Acute inflammatory diseases of the abdominal cavity;
- peritonitis;
- gastrointestinal and uterine bleeding;
- Cystitis;
- Violations of water-electrolyte exchange;
- Hypersensitivity to the components of the drug.
With caution appoint with liver and / or kidney disease, during pregnancy, during breastfeeding, with conditions after cavitary operations.
PREGNANCY AND LACTATION
Caution should be given to Senade В® during pregnancy and during breastfeeding.
APPLICATION FOR FUNCTIONS OF THE LIVER
Caution prescribed for kidney disease.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Caution is prescribed for liver diseases.
APPLICATION FOR CHILDREN
The drug is used in children aged 6 years and older.
SPECIAL INSTRUCTIONS
Senade В® is not recommended for more than 2 weeks.
After taking the drug, urine can acquire a yellow-brown or red-lilac color.
Use in Pediatrics
The drug is used in children aged 6 years and older .
OVERDOSE
Symptoms: diarrhea leading to dehydration.
Treatment: increased fluid intake is usually sufficient to compensate for the loss of fluid and electrolytes. In some cases, replacement of fluid loss and electrolytes with IV infusions of plasma substitutes is required.
DRUG INTERACTION
With prolonged use of SenadГ© in high doses, it is possible to increase the action of cardiac glycosides and influence the effect of antiarrhythmic drugs in connection with the possibility of developing hypokalemia.
With simultaneous use with thiazide diuretics, GCS, licorice root preparations, the risk of hypokalemia increases.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of reach of children, dry place at a temperature of no higher than 30 В° C. Shelf life - 3 years.
