Universal reference book for medicines
Product name: SAB ® SIMPLEX (SAB ® SIMPLEX)

Active substance: simeticone

Type: Medication that reduces flatulence

Manufacturer: PFIZER (USA) manufactured by FAMAR ORLEANS (France)
Composition, form of production and packaging
Suspension for ingestion from white to gray-white, slightly viscous, with a characteristic fruity (vanilla-raspberry) smell.
100 ml

simethicone 6.919 g

(dimethicone 350: silicon dioxide, in the ratio of 92.5%: 7.5%)

[PRING] hypromellose - 1.5 g, carbomer - 0.6 g, sodium citrate dihydrate - 1 g, citric acid monohydrate - 0.5468 g, vanilla flavor - 0.315 g, raspberry aroma - 0.108 g, sodium cyclamate - 0.2 g, sodium saccharinate - 0.02 g , sodium benzoate - 0.1 g, esters of polyglycostearic acid - 1.0378 g, sorbic acid - 0.0347 g, water - 89.6189 g.

30 ml - a bottle of a dropper of dark glass (25 drops in 1 ml) (1) - packs cardboard.


Description of the drug approved by the manufacturer for the printed edition of 2015.


A drug that reduces flatulence.
Simethicone reduces the surface tension of gas bubbles formed in the contents of the stomach and mucus of the intestine, and causes their destruction. The released gases are absorbed by the intestinal wall or removed during peristalsis of the intestine.
When ultrasound and radiography prevents interference and overlapping images;
promotes better irrigation of the mucous membrane of the colon with a contrast medium, preventing the rupture of the contrast film.
Simethicone removes foam by physical means, does not enter into chemical reactions.


Due to physical and chemical inertness it is not absorbed in the body.
After passing through the gastrointestinal tract is withdrawn in unchanged form.

- as a symptomatic therapy for increased gas production, flatulence (including in the postoperative period);

- preparation for diagnostic tests of the digestive tract (radiography, ultrasound, esophagogastroduodenoscopy);

- Acute poisoning with detergents when they get into the stomach.


The drug is taken orally.

Increased gas formation

Newborns and infants (under 1 year) who are on artificial feeding , add 15 drops (0.6 ml) of the suspension to each bottle of baby food.
The drug is well mixed with other liquids (including with milk). Sab ® Simplex can be given to newborns before feeding with a teaspoon.
Children aged 1 to 6 years are prescribed 15 drops (0.6 ml) during or after meals, and if necessary, 15 drops more per night.

Children aged 6 to 15 years are prescribed 20-30 drops (0.8-0.12 ml), adults - 30-45 drops (1.2-1.8 ml).
A single dose is taken every 4-6 hours. If necessary, it is possible to increase the single dose.
SAB ® Simplex is best taken during or after a meal and, if necessary, before going to bed.

The duration of application depends on the dynamics of complaints.
If necessary, long-term therapy is possible.
Before use, shake the bottle vigorously.
To start the suspension from the pipette, flip it upside down and tap on the bottom.
Preparing for diagnostic tests of the digestive tract

Application in preparation for diagnostic studies of the gastrointestinal tract is facilitated if the pipette is removed from the vial.

To prepare for radiography the day before the study in the evening should take 3-6 teaspoons (15-30 ml) of the drug Sab ® Simplex.

To prepare for ultrasound, it is recommended to take 3 teaspoons (15 ml) the evening of the day before the study and 3 teaspoons 3 hours before the test.

Before endoscopy should take 0.5-1 teaspoon (2.5-5 ml) and during the study through the endoscope to introduce an additional several milliliters of suspension of the drug.

Poisoning with detergents

The dose of Sab ® Simplex depends on the severity of the poisoning.
The minimum recommended dose is 1 teaspoonful (5 ml).

Possible: allergic reactions.


- Obstructive diseases of the digestive tract;

- intestinal obstruction;

- hypersensitivity to simethicone or any of the auxiliary components of the drug.


Possible use of the drug during pregnancy and lactation according to indications.


Possible use in children according to indications.


Sab ® Simplex can be used in patients with diabetes mellitus.
the drug does not contain carbohydrates.
New and / or recurring complaints associated with increased gas production should be clinically confirmed.

Impact on the ability to drive vehicles and manage mechanisms

The drug does not affect the ability to drive vehicles and work with mechanisms.


Cases of drug overdose Sab ® Simplex are not known.


The drug interaction of the drug Sab ® Simplex is not established.


The drug is approved for use as a means of OTC.


The drug should be stored out of reach of children at a temperature of no higher than 25 ° C.
Shelf life - 3 years.
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