Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
Vitamin B 2 . Regulating the oxidation-reduction processes, takes part in protein, fat and carbohydrate metabolism, as well as in maintaining the normal visual function of the eye and the synthesis of hemoglobin.
Riboflavin and its nucleotides are rapidly absorbed from the digestive tract. Chronic gastritis, enteritis, achilles slow absorption. Unevenly distributed in the organs and tissues of the body: the largest number - in the myocardium, liver, kidneys. Binding to plasma proteins - 60%. Penetrates through the placental barrier, excreted in breast milk. It is excreted by the kidneys.
Hypo-and avitaminosis B 2 , hemorrhagia, conjunctivitis, keratitis, iritis, corneal ulcer, cataracts, long-lasting non-healing wounds and ulcers, general eating disorders, radiation sickness, asthenia, intestinal dysfunction, hepatitis.
Single dose - 5-10 mg, for children - 2-5 mg 1-3 times / day for 1-1.5 months.
Possible: allergic reactions, impaired renal function, impaired vision.
Hypersensitivity to riboflavin, nephrolithiasis.
PREGNANCY AND LACTATION
Perhaps the use of riboflavin during pregnancy and lactation (breastfeeding) according to the indications.
Stains urine in a light yellow color.
At simultaneous application with m-holinoblokatorami absorption and bioavailability of riboflavin increases (due to decrease of peristalsis of the intestine).
With simultaneous use with thyroid hormones, metabolism of riboflavin is accelerated.
With simultaneous use decreases the activity of doxycycline, tetracycline, oxytetracycline, erythromycin and lincomycin.
Riboflavin is not compatible with streptomycin.
With simultaneous use, the side effects of chloramphenicol are reduced and prevented (violation of hemopoiesis, optic neuritis).
With the simultaneous use of chlorpromazine, amitriptyline due to blockade of flavinokinase disrupt the incorporation of riboflavin into flavinadenine mononucleotide and flavinadenine dinucleotide and increase its excretion in the urine.