Composition, form of production and packaging
? Suppositories vaginal from white to white with a yellowish hue of color, torpedo-shaped.
1 supp.
benzalkonium chloride 18.9 mg
Excipients: Witepsol.
5 pieces. - packings cellular planimetric (2) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2011.
PHARMACHOLOGIC EFFECT
Contraceptive drug for topical use. It has a spermatocidal effect, as well as antiseptic, antifungal, antiprotozoal action, inactivates the Herpes simplex virus.
The drug is active against gram-positive bacteria (including Staphylococcus spp., Streptococcus spp.); Gram-negative bacteria (including Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Proteus spp., Klebsiella spp.); anaerobic bacteria, fungi and molds .
Also active against strains of bacteria resistant to antibiotics and other chemotherapeutic drugs; suppresses plasmacoagulase and hyaluronidase of staphylococci.
Spermatocidal effect of the drug is due to the ability to damage the membranes of spermatozoa (at the beginning of the flagella, then the head), which makes it impossible for the egg to be fertilized by a damaged spermatozoon. The effect develops 5 minutes after the introduction of the vaginal suppository.
It is active in the prevention of sexually transmitted diseases (including gonorrhea, chlamydia, trichomoniasis). Does not affect the normal microflora of the vagina (including the wand of Dederlein) and the hormonal cycle.
PHARMACOKINETICS
The drug is not practically absorbed by intravaginal injection, it is removed simply by washing it with water and with normal physiological excretions.
INDICATIONS
Local contraception for women of reproductive age:
- if there are contraindications to the use of oral contraceptives or intrauterine contraception;
- in the postpartum period;
- during lactation;
- in the period after the termination of pregnancy;
- during the pre-menopausal period;
- if necessary, occasional protection from pregnancy;
- when you miss or late in the reception of constantly used oral contraceptives.
DOSING MODE
Preliminarily releasing the suppository from the contour pack, it is injected deep into the vagina in the supine position 5 minutes before the sexual intercourse.
Single dose: 1 suppository is designed for 1 sexual act. The duration of the drug is 4 hours.
It is obligatory to introduce a new vaginal suppository with repeated sexual acts. The frequency of use is limited by the individual tolerability of the active substance and the frequency of sexual acts.
SIDE EFFECT
Possible: allergic reactions.
CONTRAINDICATIONS
- colpitis;
- ulceration and irritation of the mucous membrane of the uterus and vagina;
- Hypersensitivity to the components of the drug.
PREGNANCY AND LACTATION
The drug has no harmful effect on the course of pregnancy.
The drug can be used during breastfeeding, as it is not excreted in breast milk.
SPECIAL INSTRUCTIONS
To increase the efficiency, careful compliance with the method of application of the preparation is necessary.
Possible application in conjunction with the vaginal diaphragm or intrauterine contraception.
After sexual intercourse, intravaginal use of hygiene products is not recommended (douching with soapy water, since soap destroys the active substance of the drug) in order to avoid loss of contraceptive effect; it is possible an external toilet of genitals.
OVERDOSE
Data on drug overdose are not provided.
DRUG INTERACTION
Any drug administered intravaginally can reduce the local spermatocidal effect (including soap and solutions containing it).
Iodine solutions (including 0.1% iodonate solution) inactivate the drug.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
List B. The drug should be stored out of reach of children, dry, protected from light at a temperature of no higher than 20 В° C. Shelf life - 2 years.
