Typical clinico-pharmacological article
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
PHARMACHOLOGIC EFFECT
Combined drug, the effect of which is due to the components that make up its composition. It has a proteolytic, amylolytic and lipolytic effect. Has a protective coating that does not dissolve before entering the small intestine, which protects the enzymes from the destructive effect of gastric juice. Promotes fast and complete digestion of food, eliminates symptoms that result from digestive disorders (feeling of heaviness and overflow of the stomach, flatulence, lack of air, shortness of breath due to the accumulation of gases in the intestines, diarrhea). Improves the process of digestion of food in children; stimulates the release of its own enzymes of the pancreas, stomach and small intestine, as well as bile. Bile extract acts choleretically, promotes fat emulsification, increases lipase activity, improves absorption of fats and fat-soluble vitamins A, E, K. Hemicellulase is an enzyme that promotes the breakdown of plant fiber.
INDICATIONS
External secretory insufficiency of the pancreas, stomach, intestines, liver, gallbladder (chronic inflammatory-dystrophic diseases of these organs, condition after resection or irradiation); flatulence, diarrhea of ​​non-infectious genesis; cystic fibrosis.
To improve the digestion of food in individuals with normal gastrointestinal function in the event of errors in nutrition (eating fatty foods, large amounts of food, irregular meals); with violations of the masticatory function (damage to the teeth and gums, during the period of getting used to the artificial jaw); sedentary lifestyle;prolonged immobilization.
Preparation for X-ray examination and ultrasound of the abdominal cavity organs. As an auxiliary drug for the early absorption of certain drugs (PASK, sulfonamides, antibiotics).
DOSING MODE
Inside, 1 dragee (enteric-coated tablets) 3 times / day during or immediately after meals. Swallowed whole, can not chew. If necessary, single dose is increased 2 times.Duration of treatment - from several days (with digestion disorders due to inaccuracies in nutrition) to several months and years (if necessary, permanent replacement therapy).
Before the X-ray examination and ultrasound - 2 dragees 2-3 times / day 2-3 days before the study.
SIDE EFFECT
Allergic reactions (skin flushing, sneezing, lacrimation), diarrhea, nausea, abdominal pain (including intestinal colic), hyperuricemia, hyperuricosuria.
In children (when taken in large doses) - perianal irritation, irritation of the mucous membrane of the oral cavity.
CONTRAINDICATIONS
Hypersensitivity; hyperbilirubinemia; acute pancreatitis, chronic pancreatitis (exacerbation), hepatitis, hepatic insufficiency, hepatic coma or precoma, empyema of the gallbladder, cholelithiasis, mechanical jaundice, intestinal obstruction.
With caution: cystic fibrosis, pregnancy; children's age (up to 3 years).
PREGNANCY AND LACTATION
With caution: pregnancy.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Contraindicated in hepatitis, liver failure, hepatic coma or precoma.
APPLICATION FOR CHILDREN
With caution: children's age (up to 3 years).
OVERDOSE
Symptoms: hyperuricemia and hyperuricuria.
Treatment: withdrawal of the drug, symptomatic therapy.
DRUG INTERACTION
Reduces the bioavailability of iron preparations
Increases the absorption of PASC, sulfonamides, antibiotics.
Cimetidine enhances the effect of the drug.
Antacids containing magnesium ions and / or calcium, reduce the effectiveness of the drug.
