Composition, form of production and packaging
? Ointment for rectal and external use is homogeneous, white with a yellowish tint, with a weak characteristic odor, which does not contain extraneous inclusions.
1 g
Benzocaine 200 mg (20%)
[PRING] shark liver oil - 30 mg (3%), mineral oil - 120 g (12%), petrolatum - 617 mg (61.7%), propylene glycol - 20 mg (2%), methylparahydroxybenzoate - 2.4 mg (0.24%) , propyl parahydroxybenzoate 0.6 mg (0.06%), sorbitan monostearate 10 mg (1%).
28.4 g - plastic tubes (1) complete with applicator - packs cardboard.
? Suppositories rectal white or white with a yellowish hue of color, in the form of a torpedo.
1 supp.
shark liver oil 60 mg (3%)
Benzocaine 206 mg (10.3%)
[PRING] cocoa bean oil, solid fat, methyl parahydroxybenzoate, propyl parahydroxybenzoate, corn starch.
6 pcs. - blisters (2) - packs of cardboard.
? Suppositories rectal white or white with a yellowish hue of color, in the form of a torpedo.
1 supp.
shark liver oil 60 mg (3%)
Benzocaine 206 mg (10.3%)
[PRING] cocoa bean oil, solid fat, methyl parahydroxybenzoate, propyl parahydroxybenzoate, corn starch.
6 pcs. - blisters (2) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2011.
PHARMACHOLOGIC EFFECT
Antihemorrhoidal drug.
Shark liver oil has anti-inflammatory, hemostatic, wound-healing and immunomodulating effects.
Benzocaine - a local anesthetic, does not have a resorptive effect.
The basis of the suppository - cocoa butter - has an additional softening effect.
PHARMACOKINETICS
Data on the pharmacokinetics of the drug Relief Advance are not available.
INDICATIONS
- external and internal hemorrhoids;
- erosion and cracks in the anus;
anal itching;
- for the purpose of anesthesia after proctologic surgeries;
- when performing diagnostic manipulations.
DOSING MODE
The drug should be used after hygienic procedures.
Suppositories are injected into the rectum in the morning, at night and after each emptying of the intestine. Adults and children over 12 years of age arerecommended to administer 1 suppository up to 4 times a day.
To apply the ointment, remove the protective cap from the applicator, attach the applicator to the tube and squeeze out a small amount of ointment to lubricate the applicator. Ointment is gently administered with the help of the applicator up to 4 times / day (in the morning, in the afternoon and in the evening and after each emptying of the intestine).
After each use, the applicator should be thoroughly rinsed and placed in a protective cap.
Children under the age of 12 years, the drug is prescribed under medical supervision.
SIDE EFFECT
Local reactions: hyperemia, itching.
Allergic reactions are possible .
CONTRAINDICATIONS
- thromboembolism;
- granulocytopenia;
- Hypersensitivity to the components of the drug.
PREGNANCY AND LACTATION
The preparation Relief Advance is used with caution during pregnancy and lactation (breastfeeding) and only if the intended benefit to the mother exceeds the potential risk to the fetus or the baby.
APPLICATION FOR CHILDREN
The question of prescribing Relief Advance for children under the age of 12 years should be decided individually, depending on the clinical situation.
SPECIAL INSTRUCTIONS
In case of accidental ingestion, immediately seek qualified help.
With abundant bloody discharge from the rectum or with painful symptoms remaining for more than 7 days, it is necessary to consult the proctologist in addition.
Use in Pediatrics
The question of prescribing Relief Advance for children under the age of 12 years should be decided individually, depending on the clinical situation.
OVERDOSE
Possible symptoms may be associated with systemic absorption of benzocaine, which is part of the drug, and include drowsiness, anxiety, agitation; in severe cases, convulsions; extremely rarely - methemoglobinemia (manifested by breathing disorders and cyanosis).
With a significant excess of the recommended single and daily doses of the shark liver oil included in the preparation, it is possible to develop a tendency to increase blood clotting.
Treatment: with methemoglobinemia - iv injection of methylene blue.
DRUG INTERACTION
The drug interaction of Relief Advance is not described.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored in a dry, protected from light, out of reach of children at a temperature of no higher than 27 В° C. Shelf life - 2 years.
