Composition, form of production and packaging
? Intestinal-coated tablets 1 dragee
pancreatin
with a minimum enzymatic activity of proteolytic lipolytic amylolytic 50 ED 3000 ED 3100 U
10 pieces. - packings of cellular contour (1) - packs cardboard.
10 pieces. - packings cellular planimetric (2) - packs cardboard.
10 pieces. - packings cellular planimetric (3) - packs cardboard.
10 pieces. - packings cellular planimetric (5) - packs cardboard.
10 pieces. - packings cellular planimetric (10) - packs cardboard.
50 pcs. - polymer cans (1) - packs of cardboard.
30 pcs. - polymer cans (1) - packs of cardboard.
50 pcs. - vials polymeric (1) - packs cardboard.
30 pcs. - vials polymeric (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2010.
PHARMACHOLOGIC EFFECT
The enzymes included in the preparation facilitate the digestion of proteins, fats and carbohydrates, which contributes to their fuller absorption in the small intestine, improve the functional state of the gastrointestinal tract, normalize the digestive processes. The maximum enzymatic activity is observed 30-45 minutes after the administration of the drug.
INDICATIONS
- substitution therapy with exocrine pancreatic insufficiency (with chronic inflammatory-dystrophic diseases, conditions after resection or irradiation);
- cystic fibrosis;
- flatulence, diarrhea of ​​non-infectious genesis;
- to improve the digestion of food in individuals with normal gastrointestinal function in the event of errors in nutrition (eating fatty foods, large amounts of food, irregular meals) and in cases of malfunctioning, sedentary lifestyle, prolonged immobilization;
- Preparation for X-ray examination and ultrasound of the abdominal cavity organs.
DOSING MODE
Inside, during or after a meal, swallowing whole, with plenty of non-alkaline liquid (water, fruit juices). The dose of the drug (in terms of lipase) depends on the age and degree of pancreatic insufficiency. The average dose for adults is 15,000 units / day; with total insufficiency of the exocrine function of the pancreas - 400,000 units / day, which corresponds to the daily needs of an adult in lipase. The maximum daily dose is 15000-20000 units / kg. In children over the age of 3 years, thedrug is prescribed by the doctor for 1-2 tablets with meals. Duration of treatment can vary from several days (with digestion disorders, due to inaccuracies in nutrition) to several months and even years (if necessary, permanent replacement therapy).
SIDE EFFECT
Rarely, diarrhea; with prolonged use in high doses - hyperuricosuria, and in patients with cystic fibrosis - strictures in the ileocecal section and in the ascending colon.Allergic reactions are possible.
CONTRAINDICATIONS
- Acute pancreatitis, exacerbation of chronic pancreatitis;
- intolerance to galactose;
- deficiency of lactase or syndrome of glucose-galactose malabsorption;
- Children's age up to 3 years;
hypersensitivity.
PREGNANCY AND LACTATION
The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the expected positive effect for the mother exceeds the potential risk to the fetus or child.
APPLICATION FOR CHILDREN
Contraindicated in children under 3 years.
OVERDOSE
Hyperuricosuria, hyperuricemia, in children - constipation.
Treatment: withdrawal of the drug, symptomatic therapy.
DRUG INTERACTION
Reduces absorption of iron preparations.
TERMS OF RELEASE FROM PHARMACY
Without recipe.
TERMS AND CONDITIONS OF STORAGE
Store in a dry, dark place at a temperature of no higher than 25 В° C. Keep out of the reach of children. Shelf life - 2 years.
