Universal reference book for medicines

Active substance: benzalkonium chloride, hypromellose

Type: Cream for moisturizing and protecting the cornea

Manufacturer: SIFI (Italy) official distributor in Russia ZAMBON (Italy)
Composition, form of production and packaging
Drops of eye
colorless or light yellow color, transparent.

1 ml

hypromellose (hydroxypropylmethylcellulose) 5 mg

benzalkonium chloride 100 Ојg

Excipients: sodium phosphate disubstituted dodecahydrate, sodium phosphate monosodium, sodium edetate, sodium chloride, purified water.

10 ml - a bottle-droppers polyethylene (1) - packs cardboard.


Description of the drug approved by the manufacturer for the printed edition of 2005.


Protector of the epithelium of the cornea.
Possessing high viscosity, increases the duration of contact of the solution with the cornea. The refractive index of the solution is similar to natural tears.
It restores, stabilizes and reproduces the optical characteristics of the tear film.
Extends the effect of other eye drops and protects the cornea from their irritating effect.

- insufficient tearing;

- Lagoftalm;

- deformation of the eyelids;

- ectropion;

- condition after plastic operations on the eyelids;

- erosion and trophic ulcers of the cornea;

- condition after chemical and thermal burns of the cornea and conjunctiva;

- bullous dystrophic changes of the cornea;

- keratopathy;

- microdefects of the epithelium of the cornea;

- condition after keratoplasty, keratoectomy;

- dry eye syndrome: Sjogren's syndrome, xerosis, keratosis (as part of combination therapy);

- eye irritation caused by smoke, dust, cold, wind, sun, salt water, allergic components;

- the need for lengthening or reducing the irritating effect of other eye drops;

- conducting diagnostic procedures: gonioscopy, electroretinography, electrooculography, ultrasound.


The drug should be instilled in 1-2 drops in the conjunctival sac 4-8 times / day.


Local reactions: the feeling of gluing the eyelids (due to the high viscosity of the solution), a feeling of burning or irritation, allergic reactions.


- acute inflammatory and infectious diseases of the anterior chamber of the eye;

- Hypersensitivity to the components of the drug.


There is no sufficient experience in the use of Lacrisifi during pregnancy and during lactation, so its use in pregnancy and lactation is possible only if the expected therapeutic effect exceeds the risk of side effects.


Lacrisifi has no sufficient experience in children, so it is possible for children to administer it only if the expected curative effect exceeds the risk of side effects.


Caution should be used Lacrisifi in the acute phase of chemical burns of the cornea and conjunctiva (until the complete removal of toxic substances and necrotic tissues).

The development of allergic reactions is possible with prolonged use of the drug.
In this case, discontinuation of treatment and the appointment of appropriate therapy are indicated.
When wearing contact lenses before instilling the drug, they should be removed and re-installed no earlier than 20-30 minutes after application of the drug.

The drug Lakrisifi is used only in ophthalmic practice, its long-term use is not recommended.
The lack of effect for a short period of time requires consultation of an ophthalmologist.
Use in Pediatrics

Lacrisifi has no sufficient experience in children, so it is possible for children to administer it only if the expected curative effect exceeds the risk of side effects.

Impact on the ability to drive vehicles and manage mechanisms

In view of possible lacrimation after instillation of the drug, it is not recommended to apply it directly before driving vehicles or servicing mechanical equipment.


There are no data on cases of Lakrisifi overdose.


The drug Lacrisifi is pharmaceutically incompatible with eye drops containing metal salts.


List B. The drug should be stored out of reach of children at a temperature of no higher than 25 В° C.
Shelf life - 4 years. After opening the vial, the drug should be used within 30 days.
Conditions of leave from pharmacies

The drug is released by prescription.

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