Composition, form of production and packaging
Eye drops 2% in the form of a clear, colorless or slightly yellowish solution.
1 ml
sodium cromoglicate 20 mg
Excipients: sodium hydrophosphate dodecahydrate, sodium dihydrogen phosphate monohydrate, polysorbate 80, sorbitol, disodium edetate dihydrate, benzalkonium chloride, purified water.
10 ml - a bottle-droppers polyethylene (1) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2015.
PHARMACHOLOGIC EFFECT
Antiallergic drug for topical application in ophthalmology. Stabilizes the membranes of mast cells and prevents the release of histamine, leukotrienes and other biologically active substances. Delayed release of mediators occurs as a result of blocking the entry of calcium ions into cells.
PHARMACOKINETICS
Absorption through the mucous membrane of the eye is negligible. Systemic bioavailability is less than 0.03%. T 1/2 - 5-10 min.
INDICATIONS
- treatment (as part of complex therapy) and prevention of allergic conjunctivitis (acute and chronic);
- for the relief and removal of irritations of the mucous membrane of the eyes, associated with allergic reactions to environmental factors and household chemicals, occupational hazards (including smoke, dust, solvents and other chemicals), the effect of cosmetics and medications, plants and pets.
DOSING MODE
When treating adults and children, instill 1-2 drops 4 times / day (up to 6 times) in the lower conjunctival sac of the affected eye at regular intervals. Duration of application of 7 days with allergic seasonal conjunctivitis and up to 4 weeks with chronic allergic conjunctivitis.
For prevention, adults and children are instilled 1 drop 4 times / day in the lower conjunctival sac of the eye, at regular intervals. The application begins 7-10 days before the possible development of seasonal allergic conjunctivitis and continues for another 7-10 days after the disappearance of the symptoms of the disease.
SIDE EFFECT
Local reactions: temporary violation of clarity of visual perception, burning sensation in the eye, superficial lesion of the epithelium of the cornea (in the drops contains a preservative - benzalkonium chloride).
Allergic reactions: itching, mild soreness and congestion hyperemia.
Other reactions: in isolated cases - nausea.
CONTRAINDICATIONS
- Children's age up to 4 years;
- Hypersensitivity to the components of the drug.
PREGNANCY AND LACTATION
Use during pregnancy and lactation is possible if the intended benefit to the mother exceeds the potential risk to the fetus and the baby. The active substance of the drug can be excreted in breast milk, but adverse effects on the baby are unlikely because of minor systemic absorption. Application in the lactation period is possible in the event that the intended benefit to the mother exceeds the potential risk for the child.
In studies on animals with parenteral administration in high doses, a decrease in the weight of the fetus was observed.
APPLICATION FOR CHILDREN
The application is possible according to the dosing regimen.
SPECIAL INSTRUCTIONS
Eye drops Crom-allergs contain preservative benzalkonium chloride, so people wearing contact lenses should remove them before applying drops and install again no earlier than 15 minutes.
Impact on the ability to drive vehicles and manage mechanisms
During the treatment with Crom-allergens, care must be taken when driving vehicles and engaging in other potentially hazardous activities requiring increased attention and speed of psychomotor reactions.
OVERDOSE
Data on drug overdose are absent.
DRUG INTERACTION
Cromoglycic acid may reduce the need for ophthalmic products containing GCS.
TERMS OF RELEASE FROM PHARMACY
The drug is released by prescription.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored in a dry, protected from light, out of reach of children, at a temperature of no higher than 25 В° C. Shelf life - 4 years.
After opening the bottle, the drops should be used within 4 weeks.
