Composition, form of production and packaging
Suppositories rectal 1 supp.
cocarboxylase hydrochloride 12.5 mg
riboflavin 1 mg
Thioctic (? -lipoic) acid 6 mg
5 pieces. - packings cellular planimetric (2) - packs cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2011.
PHARMACHOLOGIC EFFECT
Combined drug, the effect of which is determined by the effects of its constituent vitamins and coenzymes, as well as their synergistic effect.
Kokarboksilaza (coenzyme) catalyzes carboxylation and decarbobic-silylation of О±-keto acids, participates in the processes of carbohydrate metabolism. Through participation in the pentose cycle, indirectly regulates the synthesis of nucleic acids, proteins, lipids. Promotes correction of metabolic acidosis and cellular hypoxia, as well as other metabolic disorders (insufficiency of the liver, kidneys, cardiovascular system, chronic intoxication).
Riboflavin (vitamin B 2 ) as a coenzyme of flavinoproteins participates in the regulation of oxidation-reduction reactions (in the processes of carbohydrate, protein and fat metabolism). It plays an important role in the synthesis of hemoglobin and in maintaining the normal visual function of the eye, the condition of the mucous membranes and skin.
Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and other ОІ-keto acids, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of energy production in the body. Thioctic acid has a hepatoprotective effect, improves the detoxification function of the liver, protects against the effects of exo- and endotoxins.
Coripil improves tissue metabolism under various physiological and pathological conditions, requiring correction by cofactors and substrates.
INDICATIONS
The drug is indicated for use with a preventive and curative purpose in complex therapy for various pathological conditions in children, such as:
- chronic tissue hypoxia;
- decreased immunity;
- bacterial and viral infections, including acute intestinal infections;
- chronic somatic diseases;
- Chronic intoxications;
- eating disorders (hypotrophy) in children.
DOSING MODE
The drug is used rectally. Having released from the package, insert the suppository into the anus after pre-emptying the intestine.
Suppositories prescribe to children up to 1 year for 1 suppository per day.
The duration of the course of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).
SIDE EFFECT
Allergic reactions are possible - hives, itching, bronchospasm, dyspeptic phenomena.
If side effects occur, discontinue use and consult a doctor.
CONTRAINDICATIONS
Hypersensitivity reaction to the components that make up the drug.
Inflammation or bleeding in the rectum (contraindication associated with the route of administration).
APPLICATION FOR CHILDREN
The application is possible according to the dosing regimen.
SPECIAL INSTRUCTIONS
Criteria for the duration of treatment along with the clinical status are the cytochemical indices of the activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).
OVERDOSE
Cases of overdose are not described.
DRUG INTERACTION
Negative interaction was not observed. The drug can be used for complex therapy.
TERMS OF RELEASE FROM PHARMACY
The drug is released by prescription.
TERMS AND CONDITIONS OF STORAGE
In the dark place at a temperature of no higher than 20 В° C. Keep out of the reach of children.
Shelf life. 2 years. Do not use after the expiration date printed on the package.
