Universal reference book for medicines
Product name: CARIPAZYM (CARIPAZYM)

Active substance: papain

Type: Preparation with proteolytic activity for external use

Manufacturer: МЕДФЛОР�НА (Россия)
Composition, form of production and packaging
Lyophilizate for solution for external use
1 fl.

papain (papaya fruit protease) 350 PE

bottles (1) - packs of cardboard.

bottles (10) - cardboard boxes.

Lyophilizate for solution for external use 1 fl.

papain (papaya fruit protease) 700 PES

bottles (1) - packs of cardboard.

bottles (10) - cardboard boxes.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2010.

PHARMACHOLOGIC EFFECT

Proteolytic agent for external use.
It cleaves necrotic tissues, liquefies viscous secrets, exsadat. Close to the action of trypsin and chymotrypsin.
PHARMACOKINETICS

When applied externally, the drug is not absorbed and does not have systemic effects on the body.

INDICATIONS

- burns III degree (to accelerate the rejection of the scabs and to clean the granulating wounds from purulent necrotic masses).

DOSING MODE

External, in the form of solutions 35 PE / ml or 70 PE / ml, depending on the thickness of the scab.
The content of the vial is diluted in 10 ml of 0.5% solution of novocaine or 0.9% solution of sodium chloride. The solution is prepared immediately before use. A tissue moistened with a drug is applied to the burn surface, covered with a waterproof bandage, which is changed once or twice a day, removing the exfoliated necrotic tissue. At the same time, no more than 30% of the total body surface is treated. The course of treatment is from 4 to 12 days.
SIDE EFFECT

Allergic reactions.

CONTRAINDICATIONS

- pregnancy and lactation;

- Hypersensitivity to the drug.

PREGNANCY AND LACTATION

Contraindicated during pregnancy and lactation.

OVERDOSE

Cases of overdose are not described.

DRUG INTERACTION

Clinically significant interactions with other drugs have not been established.

TERMS OF RELEASE FROM PHARMACY

On prescription.

TERMS AND CONDITIONS OF STORAGE

In dry, dark place at a temperature of no higher than 15 В° C.
Keep out of the reach of children. Shelf life - 1 year 6 months.
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