Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
PHARMACHOLOGIC EFFECT
Calcium - a macronutrient involved in the formation of bone tissue, the process of blood coagulation, is necessary to maintain stable cardiac activity, the processes of transmission of nerve impulses. Improves muscle contraction in muscular dystrophy, myasthenia gravis, reduces vascular permeability. When i / in the introduction of calcium causes the excitation of the sympathetic nervous system and increased adrenal secretion of adrenaline; has a moderate diuretic effect.
When the calcium chloride solution interacts with magnesium salts, oxalic acid and fluoric acid, insoluble compounds are formed, which makes it possible to use a solution of calcium chloride as an antidote.
INDICATIONS
As an additional tool in the treatment of allergic diseases (including serum sickness, urticaria, angioedema, hay fever) and allergic reactions to medications. As an additional haemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding. As an antidote for poisoning with magnesium salts, oxalic acid and its soluble salts, as well as soluble salts of fluoric acid.
DOSING MODE
With iv introduction, a single dose is 0.5-1 mg. When administered orally, a single dose of 0.25-1.5 g. The frequency and duration of the application depends on the indications and the clinical situation.
SIDE EFFECT
Probably: a bradycardia; with rapid introduction - ventricular fibrillation; when in / in the introduction - a feeling of heat in the mouth, and then in the whole body.
CONTRAINDICATIONS
Tendency to thrombosis, severe atherosclerosis, hypercalcemia.
SPECIAL INSTRUCTIONS
Do not enter sc and v / m. When calcium chloride enters the skin or muscle tissue develops a strong irritation with the formation of foci of necrosis.
DRUG INTERACTION
Calcium chloride is incompatible with the salts of lead, silver, univalent mercury due to the formation of insoluble heavy metal chlorides and with sodium barbitol, t.while a slightly soluble calcium salt of barbitol is formed.
Calcium chloride with simultaneous application reduces the effect of calcium channel blockers. Under the influence of colestyramine, the absorption of calcium from the digestive tract decreases. With simultaneous application with quinidine, it is possible to slow intraventricular conduction and increase the toxicity of quinidine.During the treatment with cardiac glycosides, the parenteral use of calcium chloride is not recommended, due to the increased cardiotoxic effect.
