Universal reference book for medicines

Product name:

Active substance: acetylsalicylic acid

Type: NSAIDs

Manufacturer: VALENTA PHARMACEUTICS (Russia) manufactured by VITALE-XD (Estonia)
Composition, form of production and packaging
Tablets effervescent white or white with a creamy shade of color, flat-cylindrical shape, with a rough surface, with a facet and a characteristic odor, slight marble is allowed.
1 tab.

acetylsalicylic acid 324 mg

Auxiliary substances: succinic acid 0.08 g, citric acid 1.474 g, sodium bicarbonate 2.013 g, sodium benzoate 0.048 g, povidone 0.001 g, lemon flavor 0.04 g, lime flavor 0.02 g.

2 pcs.
- Strips (5) - packs of cardboard.

Description of the drug approved by the manufacturer for the printed edition of 2014.


NSAIDs of combined composition.
Acetylsalicylic acid inhibits cyclooxygenase 1 and 2, disrupting the synthesis of prostaglandins, has anti-inflammatory, antipyretic and analgesic effect, inhibits platelet aggregation.
The bicarbonate, included in the preparation of sodium, neutralizes free hydrochloric acid in the stomach, which reduces the risk of the ulcerogenic action of acetylsalicylic acid.
Citric acid promotes a faster absorption of the drug.

Data on the pharmacokinetics of Zorex Morning В® are not available.


- headache with alcohol withdrawal syndrome;

- Moderately or mildly expressed pain syndrome in adults of different origins (migraine, toothache, neuralgia, muscle pains);

- elevated body temperature for colds and other infectious and inflammatory diseases (in adults and children over 15 years old).


The drug is taken orally.
The effervescent tablet should be dissolved in a glass of water before use.
Adults and children over 15 years of age are prescribed a single dose of 1-2 tablets.
with an interval between reception 4-8 hours; the maximum daily dose is 8 tablets.
Duration of treatment should not exceed 7 days with the appointment as an anesthetic and 3 days - as an antipyretic.


On the part of the digestive system: decreased appetite, abdominal pain, gastralgia, nausea, vomiting, diarrhea, obvious (black stools, bloody vomiting) or hidden signs of gastrointestinal bleeding that can lead to iron deficiency anemia, erosive-ulcerative gastrointestinal lesions including perforations);
rarely - violations of the liver (increased liver transaminases, hyperbilirubinemia).
From the side of the central nervous system and sensory organs: dizziness, noise in the ears;
with prolonged use - headache, visual impairment, deafness.
From the hemopoietic system and hemostasis: aplastic anemia, agranulocytosis, pancytopenia, hemorrhagic syndrome, thrombocytopenia;
at long application - depression of aggregation of thrombocytes, hypocoagulation.
From the side of the urinary system: when used in high doses - hyperoxaluria and the formation of urinary stones from calcium oxalate, damage to the glomerular apparatus of the kidneys, kidney failure;
with prolonged use - papillary necrosis.
Allergic reactions: skin rash, Quincke's edema, bronchospasm, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).


- erosive and ulcerative lesions of the gastrointestinal tract (in the phase of exacerbation), gastrointestinal bleeding;

- "aspirin" asthma;

- combined use of methotrexate in a dose of 15 mg per week or more;

- pronounced violations of the liver function;

- severe renal dysfunction;

- hemorrhagic diathesis (hemophilia, von Willebrand's disease, telangiectasia, hypoprothrombinemia, thrombocytopenia, thrombocytopenic purpura);

- exfoliating aortic aneurysm;

- deficiency of glucose-6-phosphate dehydrogenase;

- portal hypertension;

- pregnancy (I and III trimester),

- lactation period;

- Hypersensitivity to acetylsalicylic acid and other NSAIDs.

The drug is not prescribed as an antipyretic agent for children under 15 with acute respiratory infections caused by viruses, because of the risk of developing Reye's syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure).

With caution should be used in hyperuricemia, urate nephrolithiasis, gout, peptic ulcer and / or duodenal ulcer (in the anamnesis), decompensated heart failure.


Contraindicated use of the drug in the I and III trimesters of pregnancy.
In the second trimester of pregnancy, one-time intake of the drug at recommended doses is possible only if the expected benefit to the mother does not exceed the potential risk to the fetus.
If you need to use the drug during lactation, breastfeeding should be discontinued.


Contraindicated use of the drug in severe violations of kidney function.


Contraindicated use of the drug in severe violations of liver function.


The drug is not prescribed as an antipyretic agent for children under 15 with acute respiratory infections caused by viruses, because of the risk of developing Reye's syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure).


Acetylsalicylic acid in low doses reduces the excretion of uric acid from the body, which can cause an acute attack of gout in predisposed patients.

With prolonged use of the drug should periodically monitor the peripheral blood, the functional state of the liver and conduct a feces analysis for latent blood.

In the case of an imminent surgical intervention, the patient must warn the doctor in advance about taking the drug.

During treatment, you should stop using alcohol (increased risk of gastrointestinal bleeding).

One dose of the drug contains 933 mg of sodium, which should be taken into account in patients on a salt-free diet.


Symptoms: in the initial stage of poisoning - CNS stimulation, dizziness, severe headache, gastralgia, ringing in the ears, decreased hearing acuity, visual impairment, nausea, vomiting, shortness of breath.
Later there comes drowsiness, convulsions, anuria, depression of consciousness down to coma, respiratory insufficiency, disturbance of water-electrolyte metabolism.
Treatment: In case of signs of poisoning, you should induce vomiting or rinse the stomach, prescribe activated charcoal and laxative, and consult a doctor.
Treatment should be carried out in a specialized department.

Increases the toxicity of methotrexate, the effect of opioid analgesics, other NSAIDs, heparin, indirect anticoagulants, thrombolytic agents and platelet aggregation inhibitors, sulfonamides (including co-trimoxazole), triiodothyronine, reserpine;
reduces the effects of uricosuric drugs (benzbromarone, sulfinpyrazone), hypotensive drugs and diuretics (spironolactone, furosemide).
SCS, ethanol and ethanol containing drugs increase the damaging effect on the gastrointestinal mucosa, increase the risk of developing gastrointestinal bleeding.

Increases the concentration of digoxin, barbiturates, and lithium preparations in blood plasma.

Antatsida, containing magnesium and / or aluminum hydroxide, slow down and worsen the absorption of acetylsalicylic acid.


The drug is approved for use as a means of OTC.


The drug should be stored in a dry, protected from light and out of reach of children at a temperature of no higher than 25 В° C.
Shelf life - 3 years.
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