Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
PHARMACHOLOGIC EFFECT
Antianemic agent containing iron. Iron is a microelement that is part of hemoglobin, myoglobin, some enzymes. Reversibly binds oxygen, participates in a number of oxidation-reduction reactions, stimulates erythropoiesis.
PHARMACOKINETICS
After ingestion, iron is absorbed completely completely from the digestive tract. C max iron in blood plasma is reached within 2-4 hours.
INDICATIONS
Treatment and prevention of iron deficiency anemia of various genesis in adults and children; violations of absorption of iron from the digestive tract.
Conditions accompanied by an increased body requirement for iron (pregnancy, lactation, active growth period, malnutrition, certain stages of treatment of B12-deficient anemia, chronic gastritis with secretory insufficiency, condition after gastrectomy, peptic ulcer of the stomach and duodenum in the acute phase; in premature infants, a decrease in the body's resistance in adults and children with infectious diseases, tumors).
DOSING MODE
When administered orally, the minimum effective dose of elemental iron for adults is 100 mg. The maximum dose is 300-400 mg.
When used for the purpose of prevention, the dose of elemental iron is 30-60 mg / day.
SIDE EFFECT
From the digestive system: rarely - a feeling of heaviness in the epigastric region, flatulence, constipation or diarrhea, disappearing with a decrease in dose.
CONTRAINDICATIONS
Aplastic and hemolytic anemia; hemochromatosis, hemosiderosis; sideroahrestic anemia, anemia in lead poisoning, thalassemia; Other types of anemia not associated with iron deficiency in the body.
PREGNANCY AND LACTATION
During pregnancy and during lactation, it is possible to use according to the indications.
SPECIAL INSTRUCTIONS
Use with caution in peptic ulcer, regional enteritis, ulcerative colitis.
The combination of iron and folic acid salts is more preferable for iron deficiency anemia with folic acid deficiency.
When the course is used, systematic monitoring of serum iron and hemoglobin levels is necessary.
DRUG INTERACTION
Under the influence of ascorbic acid, trivalent iron is converted into bivalent iron, which improves its absorption.
With the simultaneous use of iron sulfate and antacid agents containing aluminum, magnesium, calcium, as well as with colestyramine, penicillamine, iron absorption from the gastrointestinal tract decreases.
With the simultaneous use of iron sulfate and antibiotics of the tetracycline group, complex compounds are formed, which reduce the absorption of iron and antibiotics.
With the simultaneous use of iron sulfate c GCS, it is possible to enhance the stimulation of erythropoiesis.
