Composition, form of production and packaging
Solution for infusions is transparent, light yellow or yellow.
100 ml
povidone (polyvinylpyrrolidone) low molecular weight medical with a molecular weight of 8000 В± 2000 6 g
sodium chloride 550 mg
potassium chloride 42 mg
calcium chloride 50 mg
sodium hydrogen carbonate 23 mg
magnesium chloride anhydrous 500 Ојg
Auxiliary substances: water d / and.
100 ml - bottles (1) - packs of cardboard.
200 ml - bottles (1) - packs of cardboard.
250 ml - bottles (1) - packs of cardboard.
400 ml - bottles (1) - packs of cardboard.
500 ml - bottles (1) - packs of cardboard.
100 ml - bottles (28) - packs of cardboard.
200 ml - bottles (28) - packs of cardboard.
400 ml - bottles (15) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2010.
PHARMACHOLOGIC EFFECT
The action of Hemodesa-H is due to the ability of low molecular weight polyvinylpyrrolidone to bind toxins circulating in the blood and quickly remove them from the body. Hemodez-H differs from Hemodesa by a lower molecular weight of polyvinylpyrrolidone. The decrease in the molecular weight of the polymer accelerates the excretion of it by the kidneys from the body and improves the detoxification properties of the preparation. It increases renal blood flow, increases glomerular filtration and increases diuresis.
PHARMACOKINETICS
Metabolic transformations in the body are not affected. Quickly excreted by the kidneys, and for 4 hours 80% are output, and after 12-24 hours - completely.
INDICATIONS
- shock (post-traumatic, postoperative, burn, hemorrhagic),
- intoxication (toxic diseases of the digestive tract, dysentery, dyspepsia, salmonellosis);
- as a means of detoxification in the postoperative period with peritonitis;
- liver disease, accompanied by the development of liver failure;
- intestinal obstruction;
- thyrotoxicosis;
- burn disease;
acute radiation sickness;
- sepsis;
- pneumonia;
- acute phase of myocardial infarction;
- hemolytic disease of newborns;
- intrauterine infection and toxemia of newborns;
- Toxicosis of pregnant women.
DOSING MODE
Intravenously drip (40 - 80 cal / min), through a device with a filter.
The dose depends on the age of the patient and the severity of intoxication. Single dose for adults - 200-500 ml; for children - 5-10 ml / kg; the maximum single dose for infants is 50-70 ml, 2-5 years - 100 ml, 5-10 years -150 ml, 10-15 years - 200 ml. The drug is administered once or repeatedly (up to 2 times a day) for 1-10 days, depending on the severity of intoxication. In acute gastrointestinal infections, burn and radiation diseases are administered 1-2 times / day; with hemolytic disease and toxemia of newborns - 2-8 times / day (daily or every other day); with large focal myocardial infarction (in 1 day) - 200 ml once, with complications for 2 days - 200 ml
SIDE EFFECT
With the slow administration of Haemodesu-H, complications do not usually arise. Introduction with increased speed can cause a decrease in blood pressure, tachycardia, difficulty breathing and require the introduction of vasoconstrictor and cardiac agents, calcium chloride. Individual patients may experience allergic reactions, up to the development of anaphylactic shock. In these cases, you should immediately stop the infusion, conduct symptomatic therapy (introduce antihistamines, cardiotonic drugs, glucocorticoids, vasopressive drugs).
CONTRAINDICATIONS
- intracranial hypertension;
- hemorrhagic stroke;
- condition after traumatic brain injury;
- cardiovascular insufficiency IIb-III degree;
- respiratory insufficiency;
- severe allergic reactions;
- thromboembolism;
- oliguria;
anuria;
- acute nephritis;
- bronchial asthma;
- phlebothrombosis;
- Hypersensitivity to the drug.
APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindicated in acute nephritis, oliguria, anuria.
APPLICATION FOR CHILDREN
Single dose for children - 5-10 ml / kg; the maximum single dose for infants is 50-70 ml, 2-5 years - 100 ml, 5-10 years -150 ml, 10-15 years - 200 ml.
SPECIAL INSTRUCTIONS
With extensive burns combined with the introduction of plasma, albumin, gamma globulin.
Before starting the infusion, the doctor must check the integrity and integrity of the package. The drug should be clear, free of sediment, sediment and mold. The results of a visual examination are recorded in the medical history.
Before administration, the solution is warmed to body temperature.
OVERDOSE
In case of an overdose, the drug should be withdrawn and symptomatic therapy administered
TERMS OF RELEASE FROM PHARMACY
On prescription.
TERMS AND CONDITIONS OF STORAGE
Store in a dry place at a temperature not exceeding 25 В° C in places inaccessible to children. Shelf life - 3 years.
Freezing the drug is not a contraindication to its use.
Non-wetting of the inner surface of bottles is not a contraindication to the use of the drug.
