Composition, form of production and packaging
? Suspension for oral administration of 1 ml of 1 pack.
simradrate * (magnesium-aluminum-silicate in the form of hydrate) 172 mg 2.064 g
12 ml - bags of paper laminated (20) - packs of cardboard.
* - the non-proprietary international name recommended by WHO, in the Russian Federation the international name "Simaldrat" is accepted.
Gelusil lacquer
? Tablets are yellowish white, round, flat-cylindrical, with a smooth surface, with a facet on both sides, with the smell of vanilla.
1 tab.
simaldrate (aluminum-magnesium silicate in hydrate form) 500 mg
Excipients: milk powder, sucrose, magnesium stearate, vanilla flavoring 39774, lactose monohydrate, vanilla tincture.
10 pieces. - blisters (4) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2008.
PHARMACHOLOGIC EFFECT
Antacid preparation. Neutralizes excess hydrochloric acid in the stomach, has an enveloping and adsorbing effect. Prevents the influence of aggressive factors on the mucous membrane of the stomach and duodenum, has antitoxic properties. Does not cause secondary hypersecretion and does not affect the motility of the gastrointestinal tract.
PHARMACOKINETICS
Data on the pharmacokinetics of the drug are not available.
INDICATIONS
- Acute gastritis with increased and normal secretion;
- chronic gastritis with increased and normal secretion in the exacerbation phase;
acute duodenitis;
- Stomach ulcer and duodenal ulcer in the phase of exacerbation;
- hernia of the esophageal aperture of the diaphragm;
- reflux esophagitis;
- discomfort or epigastric pain, heartburn, acidic eructations after excessive consumption of alcohol, nicotine, coffee, medication, inaccuracies in the diet.
DOSING MODE
The drug is administered orally 1 tablet. or 1 packet of suspension 3-6 times / day.
Tablets are chewed or resorbed after 1 hour after ingestion.
Suspension for oral administration is taken 1-2 hours after meals and at bedtime.
If necessary, episodic use (for discomfort after inaccuracies in the diet) take 1 tab. or 1 packet of suspension once.
SIDE EFFECT
On the part of the digestive system: rarely - nausea, vomiting, constipation, diarrhea, changes in taste.
From the side of the urinary system: with prolonged use in high doses - hypercalciuria, nephrocalcinosis, renal failure.
From the side of metabolism: with prolonged use in high doses - hypermagnesia, hypocalcemia, hypercalciuria, hyperaluminia.
Other: rarely allergic reactions; with prolonged use in high doses - osteomalacia, osteoporosis, encephalopathy.
CONTRAINDICATIONS
- severe renal dysfunction;
- Hypersensitivity to the drug.
PREGNANCY AND LACTATION
The use of the drug during pregnancy and lactation (breastfeeding) is not recommended.
APPLICATION FOR FUNCTIONS OF THE LIVER
The drug is contraindicated in severe impairment of kidney function.
In patients with impaired renal function in the appointment of Gelusil should regularly monitor the content of magnesium in the serum and avoid prolonged use in high doses.
SPECIAL INSTRUCTIONS
In patients with impaired renal function in the appointment of Gelusil should regularly monitor the content of magnesium in the serum and avoid prolonged use in high doses.
When the drug is used together with citrus juices (especially grapefruit), the probability of hypermagnesemia increases.
The interval between taking Gelusil and other medications should be at least 2 hours.
Use in Pediatrics
It is not recommended to prescribe the drug to children under 10 years of age .
OVERDOSE
Data on an overdose of Gelusil is not available.
DRUG INTERACTION
With simultaneous administration of Gelusil reduces the absorption of tetracyclines, propranolol, isoniazid, iron preparations, indomethacin, salicylates.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug in the form of tablets should be stored in a place protected from light and moisture out of reach of children at a temperature of 15 В° to 25 В° C. Shelf life - 5 years.
The drug in the form of a suspension for oral administration should be stored out of the reach of children at a temperature of 15 В° to 25 В° C. Shelf life - 3 years.
