Composition, form of production and packaging
The tablets, covered with an enteric-dissolvable shell of shiny, the contents of the tablet in the form of a greyish-yellow mass, without taste and smell.
vaccine for the prevention of cholera (a mixture of cholerogen-toxoid and O-antigens obtained from formalin-inactivated broth cultures of V. cholerae O1 of the classical biowar of strains 569 B or KM-76 (569 pCO107-2) of Inab and M-41 serovar Ogawa by isolating , purification and concentration with ammonium sulfate)
Excipients: sucrose, starch, talc, calcium stearate.
Ingredients of enteric coating: cellacephate.
210 pcs. - bottles (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2014.
PHARMACHOLOGIC EFFECT
The vaccine causes in vaccinated the development of anti-cholera immunity lasting up to 6 months.
INDICATIONS
Prevention of cholera in adults, adolescents and children from 2 years of age.
Inoculations are subject to:
- persons traveling to countries unfavorable for cholera (in agreement with the Federal Service for Supervision of Consumer Rights Protection and Human Welfare);
- the population of the border regions of Russia in the event of an unfavorable situation in the adjacent territory on the cholera (by the decision of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare).
DOSING MODE
One inoculation dose of the drug is for adults - 3 tablets, adolescents 11-17 years - 2 tablets, children 2-10 years - 1 tablet.
Tablets of a cholera vaccine are taken orally 1 h before meals, swallowing whole, without chewing, washing 1/8 - 1/4 cup of boiled water.
Revaccination is performed 6-7 months after vaccination; The dose for adults and teenagers is 2 tablets, for children 2-10 years - 1 tablet.
A vaccine whose package integrity is damaged or missing information on labels, with a changed appearance of tablets (integrity disorder, discoloration), with expired shelf life, is not to be taken for use.
The drug can be taken simultaneously (on the same day) with the introduction of inactivated vaccines of the National calendar of preventive vaccinations and the calendar of preventive vaccinations for epidemiological indications (with the exception of rabies vaccines and BCG vaccine).
Precautions for use
It is not recommended to combine the reception of cholera vaccine tablets with the introduction of rabies vaccines and BCG vaccine.
SIDE EFFECT
In 1-2 hours after taking the vaccine, some grafts may develop weak unpleasant sensations in the epigastric region, rumbling in the abdomen, a mushy stool.
CONTRAINDICATIONS
- acute infectious and non-infectious diseases, including intestinal dysfunction, chronic diseases in the acute stage; Inoculations are given no earlier than 1 month after recovery (remission);
- malignant neoplasms and malignant diseases of the blood;
- immunodeficiency states;
- Pregnancy.
In order to identify contraindications, the doctor (paramedic) spends on the day of vaccination a survey and examination of vaccinated patients with mandatory thermometry.
PREGNANCY AND LACTATION
Contraindicated in pregnancy.
APPLICATION FOR CHILDREN
Children under the age of 2 are subject to vaccination.
DRUG INTERACTION
Interaction with other drugs has not been established.
TERMS OF RELEASE FROM PHARMACY
For treatment and preventive and sanitary facilities.
TERMS AND CONDITIONS OF STORAGE
Store in accordance with SP 3.3.2.1248-03 at a temperature of 0 to 8 В° C in a place inaccessible to children. Shelf life - 3 years.
