Universal reference book for medicines
Product name: CANDID (CANDID)

Active substance: clotrimazole

Type: Antifungal medication for external use

Manufacturer: GLENMARK PHARMACEUTICALS (India)
Composition, form of production and packaging
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Powder for external use from white to light yellow color, with a characteristic odor.
1 g

clotrimazole 10 mg

Excipients: talc purified - 925 mg, corn starch - 50 mg, silicon dioxide colloid - 10 mg, perfume cosmetic - 5 mg.

30 g - plastic bottles (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

Antifungal preparation of a wide spectrum of action for external application, an imidazole derivative.
Antimycotic effect associated with a violation of the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes a change in its structure and properties and leads to lysis of the cell.
To clotrimazole sensitive dermatophytes, yeast-like fungi (the genus Candida, Torulopsis glabrata, Rhodotorula), mold fungi, as well as the causative agent of the varicoloured Pityriasis versicolor and the causative agent of erythrasma.

Has antimicrobial effect against gram-positive (staphylococcus and streptococcus) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis), and also against Trichomonas vaginalis.

PHARMACOKINETICS

Clotrimazole is poorly absorbed through the skin and mucous membranes and has virtually no systemic effect.

With external application, the concentration of clotrimazole in the epidermis is higher than in the dermis and subcutaneous tissue.

INDICATIONS

- fungal skin infections;

- interdigital fungal erosion;

- Mycoses complicated by a secondary infection;

- colored lichen;

- Erythrazm.

DOSING MODE

Outwardly.
The powder is applied to the affected area of ​​the skin 3-4 times / day. Improvement of the condition occurs within 3-5 days. For successful treatment, regular use of the drug is important. The duration of therapy is individual and depends on the severity and localization of the disease. To achieve full recovery, the drug should not be discontinued immediately after the acute symptoms of inflammation or subjective complaints have disappeared.
The duration of therapy should be, on average, about 4 weeks;
with pityriasis deprivation 1-3 weeks, with erythrasma 2-4 weeks. With interdigital fungal foot erosions, it is recommended to continue therapy for about 2 weeks after relief of the symptoms of the disease.
SIDE EFFECT

Local reactions: rarely - burning, tingling at the site of application, erythema, the appearance of blisters, swelling, irritation, peeling.

Allergic reactions: itching, hives are possible.

CONTRAINDICATIONS

- I trimester of pregnancy;

- Hypersensitivity to clotrimazole or excipients.

With caution should prescribe the drug during lactation.

PREGNANCY AND LACTATION

It is not recommended to use the drug in the first trimester of pregnancy.
The question of the expediency of prescribing the drug in the II and III trimesters should be addressed individually after consultation of the doctor.
In clinical and experimental studies, a negative effect on the health of a woman or fetus is not established.

OVERDOSE

At present, no cases of an overdose of Candide have been reported.

DRUG INTERACTION

Clotrimazole reduces the activity of amphotericin B and other polyene antibiotics.

When used simultaneously with natamycin and nystatin, the activity of clotrimazole may decrease.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of no higher than 25 ° C.
Shelf life - 4 years.
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