Yohimbin (yohimbine)

YOHIMBIN (Yohimbine).
     Methyl ester gidroksiiohimban 17 A-16 A-carboxylic acid.
     Available as hydrochloride.
     Synonyms : Aphrodine, Iohimbina, Quebrachin, Yohimvetol.
     Alkaloid, dedicated the first time in 1896 from the West African tree bark Corynanthus yohimbine (Yambehou) -Pausinystalia yohymbe, a 1950 city-roots Rauwolfia.
     A derivative indolilalkilaminnoe as having similarities with rezerpinom.
     Is electoral competition A2- adrenoreceptor antagonist (klonidina- klofelina antagonist). Activates adrenergicheskie processes in the central nervous system, increasing the frequency of heart, increases motor activity was tremor. Has moderate stimulus to the spinal cord reflexes.
     Long suggested as a means of encouraging sexual activity (based on the fact that the infusion tree bark Yambehou Aborigines used for this purpose). Experimental and clinical studies of this, but not confirmed. Nevertheless, in late 1980 - ies. yohimbin again proposed for use in the treatment of neurogenic dysfunction, as well as the climax for men.
     Quickly and completely absorbed in the digestive tract, C max at 1.3 h, T1 / 2 in the plasma of 40 minutes, easily penetrates the central nervous system; Metabolised in the liver.
     Assign inwards in the form of tablets 0,005-0,01 g (5-10 mg) 1-3 times daily for 3-10 months. If necessary, repeat the course (with an interval of 10 weeks).
     Apply yohimbin (and other "afrodizika") should be appointed and supervised by a doctor.
     Possible side effects : initiation, tremor, headache, tachycardia, arterial hypotension.
     The drug is not suitable for arterial hypotension and renal function violation.
     Product : pills to 0,005 grams (5 mg) (N 20, 100).

Materials allowed to copy only with the active hyperlink to the handbook of medicines
of drugs
Index medicines

Index medicines

A  B  C  D  E  F
G  H  I  J  K  L
M  N  O  P  Q  R
S  T  U  V  W  Y Z

The page is translated by:
Google Translate