Universal reference book for medicines
Product name: EXODERIL ® (EXODERIL ® )

Active substance: naftifine

Type: Antifungal medication for external use

Manufacturer: SANDOZ (Austria) manufactured by GLOBOPHARM Pharmazeutische Productions und Handels (Austria)
Composition, form of production and packaging

The solution for external use is transparent, colorless or slightly yellow in color, with the smell of ethanol.
1 ml

naftifin hydrochloride 10 mg

Excipients: propylene glycol - 50 mg, ethanol - 400 mg, purified water - 475 mg.

10 ml - vials of dark glass with a stopper-dropper (1) - packs cardboard.

20 ml - bottles of dark glass with a stopper-dropper (1) - packs cardboard.

30 ml - bottles of dark glass with cork-dropper (1) - packs of cardboard.


Description of the drug approved by the manufacturer for the printed edition of 2017.


Antifungal drug for external use from the group of allylamines.
The mechanism of action is associated with inhibition of the synthesis of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus.
The drug is active against dermatophytes Trichophyton, Epidermophyton, Microsporum, yeast (Candida spp., Pityrosporum), mold fungi (Aspergillus spp.) And other fungi (Sporotrix schenckii).
With respect to dermatophytes and aspergillus, naphthyfine acts fungicidally. With regard to yeast fungi shows fungicidal or fungistatic activity, depending on the strain of the microorganism. The drug has antibacterial action against gram-positive and gram-negative microorganisms, which can cause secondary bacterial infections.
The drug has an anti-inflammatory effect that contributes to the rapid disappearance of symptoms of inflammation, especially itching.


Naphthyfine quickly penetrates the skin, creating stable antifungal concentrations in its various layers, which makes it possible to use it once or twice a day.


- fungal infections of skin and skin folds (tinea corporis, tinea inguinalis), incl.
interdigital mycoses (tinea manum, tinea pedum);
- fungal infections of the nails (onychomycosis);

- Candidiasis of the skin;

- pityriasis vulgaris;

- dermatomycosis (with or without accompanying itching).

Exoderyl ® is effective in the treatment of fungal infections affecting the skin area with hyperkeratosis, as well as in the hair growth zone.


Exoderyl ® should be applied to the affected skin and adjacent areas 1 time / day, after thorough cleaning and drying, taking approximately 1 cm of healthy skin at the edges of the affected area.

Duration of treatment for dermatomycosis - 2-4 weeks (if necessary - up to 8 weeks), with candidiasis - 4 weeks.

With onychomycosis before the first application of the solution, it is necessary to remove the affected part of the nail as much as possible with scissors and a nail file.The drug should be applied 2 times / day, the duration of treatment - up to 6 months.

To prevent recurrence of infection , therapy should be given for at least 2 weeks after the disappearance of clinical symptoms.


Local reactions: in some cases - dry skin, hyperemia, burning.

Side effects are reversible and do not require discontinuation of therapy.


- Pregnancy (safety and efficacy not determined);

- lactation period (safety and efficacy not determined);

- hypersensitivity to naphthiphyrene or propylene glycol.

Contraindicated application of the drug on the wound surface.

With caution: child age (experience in clinical use is limited).


Contraindicated in the use of Exozderyl ® during pregnancy and lactation (safety and efficacy not determined).


With caution : child age (experience in clinical use is limited).


The drug is not intended for use in ophthalmology.
Avoid contact with the eyes.
No special measures are required to destroy the drug.

Impact on the ability to drive vehicles and manage mechanisms

The drug does not adversely affect the ability to drive vehicles and perform other activities that require concentration and speed of psychomotor reactions.


No cases of overdose have been reported.


There was no drug interaction between the drug Exoderyl ® and other drugs.


The drug is approved for use as a means of OTC.



The drug should be stored out of reach of children at a temperature of no higher than 30 ° C.
Shelf life - 5 years.
Alphabetical index of medicines:
A  B  V  G  D  E  J
Z  I  Y  K  L  M  N
O  P  R  S  T  U  F
H  C  CH  SH  E  U  Y
Privacy policy:
Copyright 2009 - 2017. Universal reference book of medicines. All rights reserved.
When using site materials, an active hyperlink is required!