Universal reference book for medicines
Name of the preparation: FTIVAZIDE (FTIVAZIDE)

Active substance: ftivazide

Type: Anti-TB drug

Manufacturer: AVEKSIMA (Russia) manufactured by IRBITSK HFZ (Russia)
Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Anti-tuberculosis agent, derivative of hydrazide isonicotinic acid.
Has a high selective activity against Mycobacterium tuberculosis. It causes damage to the membrane of mycobacteria, inhibits metabolic and oxidative processes, inhibits the synthesis of nucleic acids, acts on mycobacteria both inside the cell and outside it.
Slowly absorbed from the digestive tract.

INDICATIONS
Treatment of active tuberculosis of all forms and localizations in adults and children.

DOSING MODE
Is taken internally.
Adults - 500 mg 2-3 times / day. Children - at a rate of 30-40 mg / kg / day in 3 divided doses. In case of tuberculous lupus - 250-300 mg 3-4 times / day. On the course - 40-60 g. If necessary, the course of treatment is repeated 2-3 times with a monthly break.
Maximum doses: for adults, single- dose - 1 g, daily - 2 g;
for children daily - 1.5 g.
SIDE EFFECT
From the central nervous system and peripheral nervous system: headache, dizziness, euphoria, deterioration of sleep;
in rare cases - psychosis, memory impairment, peripheral neuritis, optic neuritis; In patients with epilepsy, convulsive seizures may become more frequent.
On the part of the digestive system: nausea, vomiting, dry mouth, epigastric pain, drug-induced hepatitis.

From the endocrine system: in men - gynecomastia, in women - with menorrhagia.

Allergic reactions: cutaneous manifestations.

Other: pain in the heart.

CONTRAINDICATIONS
Angina pectoris;
decompensated heart defects; organic diseases of the central nervous system; kidney disease of a non-tubercular nature, as well as with impaired excretory function; hypersensitivity to ftivazidu.
APPLICATION FOR FUNCTIONS OF THE LIVER
Contraindicated in kidney disease of non-tubercular nature, as well as with impaired excretory function.

APPLICATION FOR CHILDREN
The application is possible according to the dosing regimen.

SPECIAL INSTRUCTIONS
During the period of treatment, periodic examination of the fundus is necessary.
To prevent the development of neuritis, vitamins B 1 and B 6 are simultaneously prescribed.
Ftyavazid can be used to treat patients with hypersensitivity to isoniazid.

The maximum efficiency is manifested with fresh, acute processes.
Penetrates through the placental barrier, excreted in breast milk.
TERMS AND CONDITIONS OF STORAGE
[MSK] 01.04 in the RK is not registered.

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