Composition, form of production and packaging
? Gel for local and external use in the form of a thick, opaque, non-flowing mass of white with a grayish tinge, with a weak specific odor.
1 package
titanium glycerophosphate aquacomplex 100%
10 g - cans of glass (1) - packs of cardboard.
10 g - cans of dark glass (1) - packs of cardboard.
10 g - cans of plastic (1) - packs of cardboard.
100 g - cans of dark glass (1) - packs of cardboard.
10 g - aluminum tubes (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2014.
PHARMACHOLOGIC EFFECT
Tysol - titanium glycerosolvata aquacomplex, is a metal complex compound.
As a metal compound Tysol is sterile and has an anti-inflammatory and antimicrobial effect. Tizol accelerates the reparative processes in the skin and reduces inflammatory phenomena (erythema, swelling, infiltration), contributes to the disappearance of itching. The presence of bound molecules of glycerol and the titanium atom in the Tysol molecule provides a protective and dehydrating, decongestant, local analgesic effect.
In the Tysol molecule, the titanium atom, chemically bound to glycerin, is the complexing center for the fragments composing the drug molecule: glycerin and water.This interaction determines the Tysol gel structure, which ensures its conductivity through biological tissues and its pharmacological properties. Tysol promotes the conduct of medicinal substances through the skin and mucous membranes.
PHARMACOKINETICS
With external application, Tysol is rapidly absorbed, distributed in the skin, subcutaneous tissue and underlying tissues. It is not metabolized. Isolated unchanged kidney 42%, through the intestine 48%, sweat glands 6.2%, through the mucous membranes of the respiratory tract 3.8%. The speed of elimination of the drug is 20-24 hours. It does not accumulate in the body.
INDICATIONS
- bursitis, arthritis, tendonitis, tendovaginitis;
- psoriasis, neurodermatitis, seborrheic eczema, dermatitis, scleroderma, red flat lichen;
- as a local radioprotector for radiation therapy;
- as a conductor of medicines.
DOSING MODE
Locally and externally.
Apply to the affected skin and mucous membranes with a thin layer 1-3 times a day. The course of treatment is individual, depends on the severity of the disease, localization and severity of the process. The effect of the drug comes during the first week of treatment. Possible repeated courses of treatment and prolonged use for 2-3 months.
When using the drug as a local radioprotective agent to protect against radiation damage, Tizol is applied a thin layer on the irradiation area before and 12 hours after the session. After application it is necessary to exclude contact with clothing, do not use occlusive dressings. If there is a local radiation reaction, the drug is used until it disappears.
SIDE EFFECT
Rarely, in the first minutes after application to the skin or mucous membranes, tingling, tingling, a feeling of tightness, passing on their own and not requiring the drug cancellation is possible. With individual sensitivity, local allergic reactions are possible. In this case, Tysol's application is stopped.
CONTRAINDICATIONS
- Hypersensitivity to Tysol;
- Acute inflammatory diseases of the skin and mucous membranes;
- purulent wounds with pronounced exudation phenomena.
PREGNANCY AND LACTATION
There is insufficient data on the use of the drug during pregnancy and lactation.
SPECIAL INSTRUCTIONS
Tysol, being a gel complex-forming system, is combined with many medicinal substances of various chemical composition and structure and can be used as a basis for preparation of soft medicinal forms.
OVERDOSE
Not registered.
DRUG INTERACTION
Not registered.
TERMS OF RELEASE FROM PHARMACY
Without recipe.
TERMS AND CONDITIONS OF STORAGE
In the dark place at a temperature of 5 to 25 В° C. In a place inaccessible to children. Shelf life - 2 years.
