Composition, form of production and packaging
Capsules hard gelatinous, в„–0, yellow; the contents of the capsules are white or white powder with a creamy shade of color, with a characteristic odor.
thiamine chloride (Vit B 1 ) 100 mg
[PRING] potato starch, refined sugar.
30 pcs. - polymer bottles.
INSTRUCTION FOR THE SPECIALIST.
The product description was approved by the manufacturer for the 2009 print edition.
Vitamin B group.
Vitamin B 1 is a coenzyme of the most important enzymes - transaldolase and transketolase, which catalyze mainly the processes of carbohydrate metabolism, has a positive effect on the conduct of nervous excitation by affecting the polarization in the region of neuromuscular synapses. It plays an important role in the carbohydrate, protein and fat metabolism, protects the cell membranes from the toxic effects of peroxidation products.
Absorption is high, throughout the small intestine. Before the absorption of thiamine, chloride is released from the bound state by digestive enzymes. In the blood, the concentration of thiamine chloride is comparatively low.
In plasma, mainly free thiamine is found, in erythrocytes and leukocytes - its phosphoric esters. Half of the total is contained in transversely striated muscles (including myocardium) and about 40% in internal organs.
Phosphorylation occurs in the liver. The most active phosphoric ester is thiamine diphosphate, which has coenzyme activity. It accumulates mainly in the liver, heart, brain, kidneys, spleen.
It is excreted through the intestines and kidneys.
- monotherapy for the treatment of hypovitaminosis and beriberi B 1 ;
- in the complex therapy of polyneuritis, dystrophic myocardial lesions, chronic liver damage, encephalopathy Wernicke (psychosis Korsakov);
- in the complex treatment of alcohol and opioid dependence.
The drug should be taken orally.
In the treatment of polyneuritis, dystrophic lesions of the myocardium, chronic liver damage is prescribed at 100 mg 1 time / day. The duration of treatment is 2-3 weeks.
In the treatment of alcohol and opioid dependence , 100 mg 2-3 times / day are prescribed. The duration of the course of treatment is 3-4 weeks.
Allergic reactions: rarely - skin itching, urticaria, angioedema.
- Hypersensitivity to the components of the drug.
PREGNANCY AND LACTATION
Data on the use of the drug during pregnancy and lactation are not provided.
There are no specific indications for the drug.
Data on drug overdose are not provided.
Data on drug interaction of the drug are not provided.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of reach of children, dry, protected from light at a temperature of 18 В° to 20 В° C. Shelf life - 3 years.