A typical clinical and pharmacological article
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..
Combined drug, has sedative, hypnotic, anxiolytic, anticonvulsant, central muscle relaxant effect.
Cyclobarbital - a hypnotic from the barbituric acid group with an average duration of action, causes sedation.
Diazepam is an anxiolytic agent (tranquilizer) of the benzodiazepine series, enhances the effects of GABA, reduces the excitability of neurons, inhibits polysynaptic spinal reflexes, and does not have a peripheral myorelaxing effect. Anxiolytic action is manifested in a decrease in emotional tension, easing anxiety, fear, anxiety.
- difficulty falling asleep;
- short-term sleep;
Individual, taking into account the patient's reaction to the drug. As a hypnotic drug - 1 / 2-1 tab. 1 hour before bedtime; as a sedative - 1 / 4-1 / 2 tab. 1-2 times / day.
Allergic reactions, drowsiness; when prescribed in high doses - fatigue, tremor, myasthenia gravis, ataxia, confusion of consciousness.
With prolonged use - addiction, drug dependence.
- liver failure;
- Myasthenia gravis;
- suicidal tendencies;
- lactation period;
- elderly age;
- Children's age (up to 1 year).
PREGNANCY AND LACTATION
Contraindications: pregnancy; lactation period.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
Contraindication is liver failure.
APPLICATION FOR CHILDREN
Contraindication - children's age (up to 1 year).
APPLICATION IN ELDERLY PATIENTS
Contraindication is old age.
Do not use in the first trimester of pregnancy, except in cases of extreme necessity.
When appointing pregnant women, it is possible to change the fetal heart rate.
With regular admission during lactation it is recommended to interrupt breastfeeding.
The risk of forming drug dependence increases with the use of large doses, a significant duration of treatment, and in patients who previously abused ethanol or sedatives. In the case of drug dependence, abrupt withdrawal is accompanied by withdrawal (headache, myalgia, anxiety, tension, confusion, irritability, in severe cases - derealization, depersonalization, hyperacusis, paresthesia in the extremities, light and tactile hypersensitivity, hallucinations and epileptic seizures).
Impact on the ability to drive vehicles and manage mechanisms
Patients who take the drug should refrain from engaging in activities that require increased attention and quick physical and mental reactions.
Strengthens the sedative effect of antipsychotic, sedative drugs, funds for general anesthesia, antidepressants, narcotic analgesics.
Inhibitors of microsomal oxidation prolong T 1/2 diazepam.
Disrupts the metabolism of phenytoin.
Incompatible with ethanol, anticoagulants, GCS, doxycycline, griseofulvin, oral contraceptives.