Composition, form of production and packaging
? Tablets are chewing from white to white with a light brown color, square, with concave surfaces, engraved "RENNIE" on both sides, with a smell of menthol.
1 tab.
calcium carbonate 680 mg
magnesium carbonate basic 80 mg
[PRING] sucrose 475 mg, corn pregelatinized corn starch 20 mg, potato starch 13 mg, talc 33.14 mg magnesium stearate 10.66 mg paraffin liquid light 5 mg, flavoring menthol (peppermint oil, maltodextrin, gum arabic, silicon dioxide) - 13 mg, lemon flavor (lemon oil, maltodextrin, water) 0.2 mg.
6 pcs. - blisters (2) - packs of cardboard.
6 pcs. - blisters (4) - packs of cardboard.
6 pcs. - blisters (6) - packs of cardboard.
6 pcs. - blisters (8) - packs of cardboard.
6 pcs. - blisters (16) - packs of cardboard.
12 pcs. - blisters (1) - packs of cardboard.
12 pcs. - blisters (2) - packs of cardboard.
12 pcs. - blisters (3) - packs of cardboard.
12 pcs. - blisters (4) - packs of cardboard.
12 pcs. - blisters (8) - packs of cardboard.
? Tablets chewing (orange) white with a creamy hue, square, with concave surfaces, engraved "RENNIE" on both sides, with the smell of orange.
1 tab.
calcium carbonate 680 mg
magnesium carbonate basic 80 mg
[PRING] sucrose 475 mg, corn pregelatinized corn starch 20 mg, potato starch 13 mg, talc 33.14 mg, magnesium stearate 10.66 mg, paraffin liquid 5 mg, orange flavoring (orange oil, maltodextrin, purified water) - 35.2 mg, sodium saccharinate - 2 mg.
6 pcs. - blisters (2) - packs of cardboard.
6 pcs. - blisters (4) - packs of cardboard.
6 pcs. - blisters (6) - packs of cardboard.
6 pcs. - blisters (8) - packs of cardboard.
6 pcs. - blisters (16) - packs of cardboard.
12 pcs. - blisters (1) - packs of cardboard.
12 pcs. - blisters (2) - packs of cardboard.
12 pcs. - blisters (3) - packs of cardboard.
12 pcs. - blisters (4) - packs of cardboard.
12 pcs. - blisters (8) - packs of cardboard.
? Tablets are chewable without sugar (mint) white with a creamy hue, square, with concave surfaces, engraved "RENNIE" on both sides, with the smell of mint.
1 tab.
calcium carbonate 680 mg
magnesium carbonate basic 80 mg
[PRING] sorbitol 400 mg, corn pregelatinized corn starch 20 mg, potato starch 13 mg, talc 35.5 mg, magnesium stearate 10.7 mg, paraffin liquid 5 mg, mint flavor 10 mg, sodium saccharinate 800 Ојg.
2 pcs. - Strips (18) - packs of cardboard.
6 pcs. - blisters (2) - packs of cardboard.
6 pcs. - blisters (4) - packs of cardboard.
6 pcs. - blisters (6) - packs of cardboard.
6 pcs. - blisters (8) - packs of cardboard.
6 pcs. - blisters (16) - packs of cardboard.
12 pcs. - blisters (1) - packs of cardboard.
12 pcs. - blisters (2) - packs of cardboard.
12 pcs. - blisters (3) - packs of cardboard.
12 pcs. - blisters (4) - packs of cardboard.
12 pcs. - blisters (8) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2017.
PHARMACHOLOGIC EFFECT
Antacid preparation. Contains calcium carbonate and magnesium carbonate, which provide rapid and prolonged neutralization of excess hydrochloric acid of gastric juice, thereby providing a protective effect on the gastric mucosa.
Achieving a therapeutic effect within 3-5 min is due to the good solubility of the tablets and the high calcium content.
PHARMACOKINETICS
Suction
As a result of the interaction of Rennie В® with gastric juice in the stomach, soluble salts of calcium and magnesium are formed. The degree of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum absorption is 10% calcium and 15-20% magnesium.
Excretion
A small amount of absorbed calcium and magnesium is excreted by the kidneys. In the intestine, soluble salts form insoluble compounds that are excreted with feces.
Pharmacokinetics in special clinical cases
If the renal function is impaired, the concentration of calcium and magnesium in the plasma may increase.
INDICATIONS
- symptoms associated with increased acidity of gastric juice and reflux esophagitis: heartburn, acidic eructation, periodic pain in the stomach, feeling of overflow or heaviness in the epigastric region, dyspepsia (including caused by inaccuracies in diet, medication, abuse alcohol, coffee, nicotine);
- dyspepsia of pregnant women.
DOSING MODE
The drug is taken orally.
Adults and children over the age of 12 with symptoms of 1-2 tablets. should be chewed (or kept in the mouth until completely dissolved). If necessary, you can repeat taking the drug after 2 hours. The maximum daily dose is 11 tab.
SIDE EFFECT
Allergic reactions: very rarely - rash, Quincke's edema, anaphylactic reactions.
When the recommended dosage is observed, the drug is well tolerated.
CONTRAINDICATIONS
- severe renal failure;
- hypercalcemia;
- hypophosphatemia;
- nephrocalcinosis;
- children's age till 12 years;
- deficiency of sugar / isomaltase, intolerance to fructose, glucose-galactose malabsorption (for chewing tablets);
- Hypersensitivity to the components of the drug.
PREGNANCY AND LACTATION
When used in recommended doses, the drug does not pose a hazard to the fetus or the baby.
APPLICATION FOR FUNCTIONS OF THE LIVER
The drug is contraindicated in patients with severe renal failure, nephrocalcinosis.
When appointing the drug, patients with impaired renal function should regularly monitor the concentration of magnesium, phosphorus and calcium in the blood serum.
Patients with impaired renal function are not recommended to take the drug for a long time in high doses.
The use of Rennie В® in high doses may increase the risk of kidney stones.
APPLICATION FOR CHILDREN
The drug is contraindicated for children under 12 years.
SPECIAL INSTRUCTIONS
When appointing the drug, patients with impaired renal function should regularly monitor the concentration of magnesium, phosphorus and calcium in the blood serum.
Patients with impaired renal function are not recommended to take the drug for a long time in high doses.
The use of Rennie В® in high doses may increase the risk of kidney stones.
Each chewable tablet / chewable tablet (orange) contains 475 mg of sucrose .
1 Rennie В® tablet without sugar (mint) contains 400 mg of sorbitol and can be administered to patients with diabetes mellitus .
If the treatment is ineffective, the patient should consult a doctor.
Impact on the ability to drive vehicles and manage mechanisms
Does not affect.
OVERDOSE
Symptoms: prolonged use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which can be manifested by nausea, vomiting, muscle weakness.
Treatment: the drug should be discontinued; the patient should consult a doctor.
DRUG INTERACTION
Changing the acidity of gastric juice, caused by the use of antacids, can lead to a decrease in the rate and degree of absorption of other drugs taken simultaneously, so drugs should be taken 1-2 hours before or after taking antacids.
With simultaneous use of antacids reduce the absorption of antibiotics of the tetracycline group, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, phosphates, fluorides.
When used simultaneously with thiazide diuretics, the concentration of calcium in serum should be monitored regularly.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of the reach of children at a temperature of no higher than 25 В° C. Shelf life: for chewing tablets - 5 years, for tablets chewing (orange), tablets chewing sugar-free (mint) - 3 years.
