Universal reference book for medicines
Product name: REMAXOL В® (REMAXOL В® )

Active substance: comb.
drug
Type: Hepatoprotector

Manufacturer: POLISAN NTFF (Russia)
Composition, form of production and packaging
Solution for infusions is
transparent, colorless, with a weak characteristic odor.

1 l

succinic acid 5.28 g

meglumine (N-methylglucamine) 8.725 g

inosine (riboxin) 2 g

methionine 0.75 g

nicotinamide 0.25 g

[PRING] sodium chloride - 6 g, potassium chloride - 0.3 g, magnesium chloride (in terms of anhydrous) - 0.12 g, sodium hydroxide - 1.788 g, water d / and - up to 1 liter.

200 ml - glass bottles (1) - packs of cardboard.

400 ml - glass bottles (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2012.

PHARMACHOLOGIC EFFECT

Balanced infusion solution, which has a hepatoprotective effect.

The preparation accelerates the transition of anaerobic processes to aerobic processes, improves the energy supply of hepatocytes, increases the synthesis of macroergic compounds, increases the stability of hepatocyte membranes to lipid peroxidation, restores the activity of antioxidant defense enzymes.
Remaxol В®reduces cytolysis, which is manifested in a decrease in indicator enzymes: ALT and AST.
Remaxol В® helps reduce bilirubin and its fractions, improves excretion of direct bilirubin in bile.
Reduces the activity of excretory enzymes of hepatocytes - alkaline phosphatase and GGT, promotes the oxidation of cholesterol to bile acids.
PHARMACOKINETICS

With IV injection, the natural components that make up the body are quickly distributed in the tissues of the body, being disposed of almost instantly.

Metabolism products are excreted in the urine and do not accumulate in the body.

INDICATIONS

- violations of the liver due to acute or chronic damage to it (toxic, alcoholic, medicinal hepatitis);

- in the complex treatment of viral hepatitis (in addition to etiotropic therapy).

DOSING MODE

Remaxol В® is administered only intravenously at a daily dose of 400 ml to 800 ml for 3-12 days, depending on the severity of the disease.
The rate of administration of 40-60 drops (2-3 ml) / min.
SIDE EFFECT

On the part of the body as a whole: with the rapid administration of the solution - hyperemia of the skin of varying severity, a feeling of heat, a sore throat, dry mouth (not requiring withdrawal of the drug).

Allergic reactions: rash and itchy skin (eliminated using antihistamines).

On the part of metabolism: a decrease in the concentration of glucose and an increase in the content of uric acid in the blood (due to the activation of the drug by aerobic processes in the body).

Other: rarely - nausea, headache and dizziness.

CONTRAINDICATIONS

- Pregnancy;

- lactation period;

- childhood;

- individual intolerance to the components of the drug.

With caution should prescribe the drug for nephrolithiasis, gout, hyperuricemia.

PREGNANCY AND LACTATION

Contraindicated use of the drug during pregnancy and lactation.

APPLICATION FOR CHILDREN

Contraindicated in childhood.

SPECIAL INSTRUCTIONS

It is not recommended to mix in one vial with other drugs for IV administration.

OVERDOSE

There is no information about drug overdose.

DRUG INTERACTION

Data on the drug interaction of Remaxol В® with other drugs are not provided.

TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a place protected from light, inaccessible to children at temperatures from 0 В° to 25 В° C.
Shelf life - 2 years.
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