Universal reference book for medicines
Product name: RELIFE В® ULTRA (RELIEF ULTRA)

Active substance: hydrocortisone, zinc sulfate

Type: Preparation with anti-inflammatory, astringent, drying and wound-healing action for topical application in proctology

Manufacturer: BAYER (Russia) manufactured by ISTITUTO de ANGELI (Italy)
Composition, form of production and packaging

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Suppositories rectal from pale yellow to light yellow, opaque, in the form of a torpedo, with the smell of fish.
1 supp.

hydrocortisone acetate 10 mg (0.5%)

zinc sulfate monohydrate 11 mg (0.55%)

[PRING] shark liver oil - 60 mg (3.0%), methylparahydroxybenzoate 0.4 mg (0.02%), propyl parahydroxybenzoate 0.4 mg (0.02%), cocoa butter 1914.2 mg (95.71%), calcium hydrophosphate anhydrous 2 mg 0.1%), magnesium stearate - 2 mg (0.1%).

6 pcs.
- blisters (2) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

Combined antihemorrhoidal drug.

Hydrocortisone acetate - steroid hormone of the adrenal cortex, with local application has anti-inflammatory, desensitizing, anti-allergic, vasoconstrictive and antipruritic effect.
Oppresses the selection of mediators of inflammation.
Zinc sulfate promotes wound healing and erosion.

Shark liver oil has anti-inflammatory, hemostatic, wound-healing, immunomodulating effect.

PHARMACOKINETICS

Data on the pharmacokinetics of Relief Ultra are not available.

INDICATIONS

- external and internal hemorrhoids;

- cracks and erosion of the anus;

- proctitis;

- anal itching, eczema and dermatitis of the perianal area.

DOSING MODE

The drug should be used after hygienic procedures.
Enter into the rectum to 1 suppository up to 4 times / day.
SIDE EFFECT

Probably: local allergic reactions (hyperemia, itching).

CONTRAINDICATIONS

- bacterial, fungal and viral infection in the zone of drug administration;

- neoplasm of the anorectal zone;

- tuberculosis;

- Itenko-Cushing syndrome;

- severe forms of diabetes mellitus;

- Hypernatremia;

- Pregnancy;

- the period of lactation (breastfeeding);

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Contraindicated use of the drug during pregnancy and lactation (breastfeeding).

SPECIAL INSTRUCTIONS

In case of severe arterial hypertension, heart rhythm disturbances, immunodeficiency states, osteoporosis, diabetes mellitus and other endocrine pathology, the use of the drug is permissible only on strict medical parameters if the expected therapeutic effect exceeds the potential risk of side effects or complications of the underlying disease.

OVERDOSE

Cases of drug overdose with disorders of vital body functions in medical practice are not described.

It is assumed that prolonged use of Relief Ultra in high doses can lead to the same consequences as systemic use in excessive doses of GCS.

Symptoms: hyperglycemia, hypernatremia, Itenko-Cushing syndrome, suppression of immunity, erosion and ulcers of the gastrointestinal tract, osteoporosis.

Treatment: withdrawal of the drug, conventional detoxification and symptomatic therapy.

DRUG INTERACTION

Data on the drug interaction of Relief Ultra is not available.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a dry, protected from light, out of reach of children at a temperature of no higher than 27 В° C.
Shelf life - 2 years.
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