Universal reference book for medicines

Active substance: neomycin, nystatin, polymyxin B

Type: The drug with antibacterial and antifungal action for topical application in gynecology

Manufacturer: Laboratoire INNOTECH INTERNATIONAL (France) manufactured by INNOTHERA CHOUZY (France)
Composition, form of production and packaging
Capsules vaginal
soft, from pale yellow to beige, oval;
the contents of the capsules are a semi-liquid homogeneous mass from yellow to brown.
1 caps.

neomycin sulfate 35,000 IU

polymyxin B sulfate 35,000 IU

nystatin 100 000 IU

Excipients: Tefoz 63 В® - 125 mg, soya hydrogenated oil - 30 mg, dimethicone 1000 - up to 2500 mg.

The composition of the capsule shell: gelatin - 381.2 mg, glycerol - 191.5 mg, dimethicone 1000 - 86.9 mg.

6 pcs.
- blisters (1) - packs of cardboard.
6 pcs.
- blisters (2) - packs of cardboard.

Description of the drug approved by the manufacturer for the printed edition of 2014.


The drug with antibacterial and antifungal action for topical application in gynecology.
Has a bactericidal effect.
Neomycin and polymyxin B are active against many Gram-positive and Gram-negative microorganisms.
Streptococcus spp. and anaerobic bacteria are insensitive to these antibiotics.
Nystatin has a fungicidal effect against fungi of the genus Candida.

The drug improves trophic processes in the mucous membrane of the vagina.


Evenly distributed on the mucous membrane of the vagina, exerting local bactericidal and fungicidal action.
Virtually not absorbed from the surface of the mucous membrane of the vagina.

Treatment of infectious-inflammatory diseases caused by sensitive microorganisms:

- nonspecific vaginitis;

- fungal vaginitis;

- mixed vaginitis;

- vulvovaginitis;

- cervicovaginitis.

Prevention of infectious complications:

- before surgical gynecological interventions;

- before and after diathermocoagulation of the cervix;

- before intrauterine diagnostic procedures;

- before giving birth.


Lying on the back, 1 capsule is injected deep into the vagina in the evening before going to bed.
The course of treatment is 12 days. Preventive course - 6 days.
If one or more doses are missed, the treatment should be resumed at the usual dose.


Possible: allergic reactions, burning, itching, irritation in the vagina;
allergic contact erythema.
With prolonged use, a systemic manifestation of side effects of aminoglycosides is possible.


- I trimester of pregnancy;

- lactation period;

- Hypersensitivity to the components of the drug.


Contraindicated use of the drug in the I trimester of pregnancy.
The use in the II and III trimesters of pregnancy is possible only according to the prescription of the doctor in those cases when the expected benefit for the mother exceeds the potential risk to the fetus.
Contraindicated in the period of lactation.
If you need to use the drug in this period, breast-feeding should be discontinued.

Before using the drug, a preliminary smear extraction and bacteriological analysis are necessary.

The timing of the drug should be limited in order to prevent the formation of resistance to it of certain pathogens and the risk of reinfection.

During treatment it is not recommended to use caps and condoms from latex.

Do not interrupt treatment during menstruation.

The patient should be warned about the need to inform the attending physician about aggravation of any of the side effects indicated in the manual or about the appearance of other side effects not indicated in the instructions.

Impact on the ability to drive vehicles and manage mechanisms

There is no evidence of a negative effect of the drug on the ability to control vehicles and other mechanisms.


At present, there have been no reports of overdose of Polizinax.


It is not recommended to use Polyinax at the same time as spermicides.
may decrease the activity of the drug.

The drug is released by prescription.


The drug should be stored out of reach of children at a temperature of no higher than 25 В° C.
Shelf life - 2 years.
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