Universal reference book for medicines

Active substance: piperazine adipate

Type: Anthelmintic preparation

Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

Anthelmintic means.
Has a paralyzing effect on nematodes, disrupting the function of their neuromuscular system.
Ascaridosis, enterobiosis.

With ascariasis, take 2 consecutive days 2 times / day for 1 hour before or 0.5-1 hours after meals in the following doses:

Patient's age Single dose

Adults 1.5-2g


13-15 years old 1.5 g

9-12 years old 1 g

6-8 years 750 mg

4-5 years 500 mg

2-3 years 300 mg

up to 1 year 200 mg

It is also possible to use for one day: once from 400 mg to 4 g (depending on age) or 2 times from 200 mg to 2 g. When enterobiosis is used in the same doses for 5 consecutive days, 1-3 cycles of treatment are administered with a 7-day break.
In between cycles it is recommended to prescribe an enema for the night (for removal of pinworm from the rectum): for adults - from 4-5 glasses of water, for children - from 1-3 glasses of water (with the addition of sodium bicarbonate 1/2 teaspoon per glass of water) .
From the digestive system: nausea, abdominal pain.

From the side of the central nervous system: a transient headache.
In patients with renal insufficiency, the drug can cause neurotoxic complications. In case of an overdose, tremors and muscle weakness are possible.
Organic diseases of the central nervous system, hypersensitivity to piperazine adipate.

The use of piperazine adipate does not require the preliminary preparation of patients and the appointment of a special diet.
Laxatives are prescribed only if prone to constipation (on the days of piperazine in the evening). In the treatment of enterobiosis, strict adherence to the hygiene regime is necessary.
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