Universal reference book for medicines
Product name: OPATANOL (OPATANOL)

Active substance: olopatadine

Type: Antiallergic drug for topical application in ophthalmology

Producer: ALKON PHARMACEUTICS (Russia) manufactured by sa ALCON-COUVREUR nv (Belgium)
Composition, form of production and packaging
Eye drops 0.1%
in the form of a clear or slightly opalescent solution, from colorless to pale yellow.

1 ml

olopatadine hydrochloride 1.11 mg,

which corresponds to the content of olopatadine 1 mg

Excipients: benzalkonium chloride, sodium chloride, disodium phosphate dodecahydrate, hydrochloric acid and / or sodium hydroxide solution (to maintain the pH level), purified water.

5 ml - a bottle of dropper plastic "Drop Tainer" (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the print edition of 2007.

PHARMACHOLOGIC EFFECT

The selective blocker of histamine H 1 -receptors also inhibits the release of inflammatory mediators from mast cells.
Has a pronounced anti-allergic effect.
Has no effect on? -adrenoceptors, dopamine receptors, m 1 - and m 2 -cholinoreceptors, as well as on serotonin receptors.

PHARMACOKINETICS

Suction

With topical application, systemic absorption is low.
C max of olopatadine in blood plasma is achieved within 2 hours after topical application and is from 0.5 ng / ml and less to 1.3 ng / ml.
Excretion

T 1/2 in plasma is 3 hours. It is excreted mainly by the kidneys, 60-70% is excreted unchanged.

INDICATIONS

allergic conjunctivitis.

DOSING MODE

The drug is instilled in 1 drop in the conjunctival sac 2 times / day.

Before use, the vial should be shaken.

SIDE EFFECT

Local reactions: less than 5% - blurred vision, burning and pain in the eyes, lacrimation, foreign body sensation in the eye, conjunctival hyperemia, keratitis, iritis, eyelid swelling.

Systemic reactions : 0.1-1% - weakness, headache, dizziness, nausea, pharyngitis, rhinitis, sinusitis, taste change.

CONTRAINDICATIONS

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

There is no sufficient experience in the use of the drug during pregnancy and lactation (breastfeeding).
Use in pregnant women and nursing mothers is possible when the expected therapeutic effect exceeds the potential risk of side effects in the fetus or infant.
APPLICATION FOR CHILDREN

Sufficient experience in the use of the drug in children under the age of 3 years is not available.
Opatanol can be administered to children aged 3 years and olderin the same doses as adults.
SPECIAL INSTRUCTIONS

Opatanol contains a preservative of benzalkonium chloride, which can be absorbed by contact lenses.
Before instillation of a preparation of a lens it is necessary to remove and establish them back not earlier than in 20 mines after instillation.
Do not touch the tip of the pipette with any surface to avoid contamination of the solution.

Use in Pediatrics

Sufficient experience in the use of the drug in children under the age of 3 years is not available.
Opatanol can be administered to children aged 3 years and olderin the same doses as adults.
Impact on the ability to drive vehicles and manage mechanisms

If the patient after application of the drug temporarily reduces the clearness of vision, then until it is restored, it is not recommended to drive the car and engage in other activities that require a high concentration of attention and speed of psychomotor reactions.

OVERDOSE

When topical application of an overdose is unlikely.
If eye contact is excessive, it is recommended to wash eyes with warm water.
DRUG INTERACTION

Compatible with other ophthalmic drugs for topical use.
If a simultaneous application is required, the interval between instillations should be at least 5 minutes.
TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

List B. The drug should be stored out of reach of children at a temperature of 4 ° to 30 ° C.
Shelf life - 3 years.
After opening the vial, the drug should be used within 4 weeks.

Alphabetical index of medicines:
A  B  V  G  D  E  J
Z  I  Y  K  L  M  N
O  P  R  S  T  U  F
H  C  CH  SH  E  U  Y
Privacy policy:
Copyright 2009 - 2017. Universal reference book of medicines. All rights reserved.
When using site materials, an active hyperlink is required!