Universal reference book for medicines
Product name: OPHTOLIKE ® (OPHTHOLIQUE)

Active substance: polyvinyl alcohol, povidone

Type: Cream for moisturizing and protecting the cornea

Manufacturer: PROMED EXPORTS (India)
Composition, form of production and packaging
Eye drops
in the form of a clear, colorless or slightly yellowish solution.

1 ml

Povidone 6 mg

polyvinyl alcohol 14 mg

Excipients: benzalkonium chloride, disodium edetate, sodium chloride, water d / and.

5 ml - a vial of a dropper plastic (1) - packs cardboard.

10 ml - a vial of a dropper plastic (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2011.

PHARMACHOLOGIC EFFECT

Keratoprotector.
The drug has a protective effect on the cornea of ​​the eye with a decreased secretion of tear fluid or increased evaporation of the tear film.
Polyvinyl alcohol and povidone have the properties of lubricant, which reduces irritation and redness of the eye.
Covering the surface of the eye, these substances reduce the stress of the surface and prevent the formation of ruptured tear film.
Polyvinyl alcohol has properties similar to the properties of mucin, produced by conjunctival glands.
It helps to soften and lubricate (moisturize) the surface of the eye, increases the stability of tear film.
PHARMACOKINETICS

Systemic absorption of the drug from the eye surface is minimal: after instillation of 2 cap.
Ophthalmic in each eye the concentration of active substances of the drug in the plasma after 4 hours remains below the possible limit of quantification (10 ng / ml).
INDICATIONS

- a feeling of burning, irritation and discomfort caused by dry eyes;

- as a substitute for tears in the case of a decrease in the secretion of tear fluid;

- dry eye syndrome;

- Other conditions requiring softening and / or moistening of the cornea.

DOSING MODE

Assign 1-2 drops 3-4 times / day in both eyes, depending on the severity of the symptoms.

Application rules

Wash hands before applying the product.
Shake the vial and remove the lid. Make sure that the tip of the pipette does not touch the skin or the surface of the eye to prevent infection of the mucous membrane. Throw back the head, pull the lower eyelid down, turn the vial and drip the necessary amount of drops into the conjunctival sac. After use, the bottle should be tightly closed with a lid.
SIDE EFFECT

Possible: allergic reactions to the components of the drug.

CONTRAINDICATIONS

- Hypersensitivity to the components of the drug.

PREGNANCY AND LACTATION

Sufficient experience in the use of the drug during pregnancy and during lactation there.

The use of the drug during pregnancy and lactation (breastfeeding) is possible only if the intended benefit to the mother exceeds the potential risk to the fetus.

SPECIAL INSTRUCTIONS

Do not use the drug if the color of the solution has changed or it has become cloudy.
In order to prevent infection of the eye mucosa, care should be taken to ensure that the pipette tip does not touch the skin, eye surface or other surfaces during application.
The patient should stop using the drug and consult a doctor if:

- with the use of drops, pain intensifies;

- eyesight deteriorates;

- symptoms persist for more than 72 hours;

redness and irritation of the eyes remain.

The drug contains benzalkonium chloride, so you can not wear contact lenses for 20 minutes after the application of drops.

OVERDOSE

Data on drug overdose are not provided.

DRUG INTERACTION

Polyvinyl alcohol undergoes an esterification reaction characteristic of compounds with secondary hydroxy groups.
It breaks down in strong acids and softens or dissolves in weak acids and alkalis. In high concentrations, polyvinyl alcohol is incompatible with inorganic salts, especially phosphates and sulphates. The formation of a 5% precipitate of polyvinyl alcohol can be caused by the reaction with phosphates. The formation of a gel from a solution of polyvinyl alcohol can occur in the presence of borax.
The solution of povidone is compatible with many inorganic salts, natural and synthetic resins and other substances.
Interacts in solution with sulfatiazole, sodium salicylate, salicylic acid, phenobarbital, tannin and other substances. The effectiveness of some preservatives (for example, thiomersal) may decrease due to the formation of complexes with povidone.
TERMS OF RELEASE FROM PHARMACY

The drug is released by prescription.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children, dry, protected from light at a temperature of no higher than 25 ° C;
Do not freeze. Shelf life - 2 years.
After opening the bottle the drug is usable for 1 month.

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