Universal reference book for medicines
Name of the drug: XIMELIN ECO WITH MENTHOL (XYMELIN ECO WITH MENTHOL)

Active substance: xylometazoline

Type: Vasoconstrictive drug for topical application in ENT practice

Manufacturer: NYCOMED AB (Sweden) manufactured by NYCOMED PHARMA (Norway)
Composition, form of production and packaging
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Spray nasal 0.1% in the form of a transparent to slightly opaque, colorless to slightly colored liquid with a smell of menthol.
1 ml

xylometazoline hydrochloride 1 mg

Excipients: sorbitol, castor hydrogenated oil, levomenthol, cineole (eucalyptol), sodium chloride, sodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate dihydrate, disodium edetate, purified water.

10 ml - plastic bottles with pump dispenser (1) - packs cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2014.

PHARMACHOLOGIC EFFECT

Vasoconstrictive drug for topical application in ENT practice, alpha-adrenomimetic.
Causes constriction of the blood vessels of the nasal mucosa, thus eliminating the edema and hyperemia of the nasopharyngeal mucosa. Relieves nasal breathing in rhinitis.
In therapeutic doses, it does not irritate the mucous membrane, it does not cause hyperemia.
The action comes in a few minutes and lasts for 10-12 hours.
PHARMACOKINETICS

With topical application is practically not absorbed, plasma concentrations are so small that they can not be determined by modern analytical methods.

INDICATIONS

- acute respiratory diseases with phenomena of rhinitis (common cold);

acute allergic rhinitis;

- Pollinosis;

- sinusitis;

- Eustachyte;

- otitis media (to reduce edema of the nasopharynx mucosa);

- Preparation of the patient for diagnostic manipulation in the nasal passages.

DOSING MODE

The drug is administered intranasally.

Adults and children older than 10 years - 1 injection in each nasal passage, if necessary, apply the drug repeatedly.
Frequency of application - no more than 3 times / day. Duration of treatment - no more than 10 days.
SIDE EFFECT

With frequent and / or prolonged use: irritation and / or dryness of the nasopharyngeal mucosa, burning, paresthesia, sneezing, hypersecretion.

Rarely: edema of the nasal mucosa, palpitations, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, impaired vision;
with prolonged use in high doses - depression.
CONTRAINDICATIONS

- arterial hypertension;

- tachycardia;

- severe atherosclerosis;

- glaucoma;

- Atrophic rhinitis;

- thyrotoxicosis;

- surgical interventions on the meninges (in the anamnesis);

- Pregnancy;

- children's age till 10 years;

- Hypersensitivity to the components of the drug.

With caution should be used in diabetes mellitus, angina pectoris of III-IV functional class, prostatic hyperplasia.

PREGNANCY AND LACTATION

Ximelin Eco with menthol is contraindicated in pregnancy.

During lactation (breastfeeding), the drug should be used only after a thorough evaluation of the expected benefit of therapy for the mother and the possible risk to the infant.
Do not exceed the recommended dose.
APPLICATION FOR CHILDREN

Contraindicated in children under 10 years.

SPECIAL INSTRUCTIONS

Do not apply Ximelin Eco with menthol for a long time, for example, with chronic rhinitis.
If the symptoms of the disease worsen or the patient's condition does not improve within 3 days of taking the drug, you should consult your doctor.
Impact on the ability to drive vehicles and manage mechanisms

Ximelin Eco with menthol does not affect the ability to drive vehicles or equipment.

OVERDOSE

Symptoms: increased side effects.

Treatment: withdrawal of the drug, symptomatic therapy.

DRUG INTERACTION

The drug is incompatible with MAO inhibitors and tricyclic antidepressants.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored out of reach of children at a temperature of no higher than 30 В° C. The shelf life is 2.5 years.

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