Universal reference book for medicines
Product name: CAROLIN (CAROLIN)

Active substance: betacarotene

Type: Vitamin preparation

Manufacturer: РОСКАРФАРМ (Russia)
Description of the active substance:
This information is a reference and it is not enough that the drug has been prescribed by a doctor ..

PHARMACHOLOGIC EFFECT
Carotenoid, a precursor of vitamin A. It has an antioxidant effect, it has the ability to inactivate free radicals under conditions of hypoxia.

Protects the skin from the harmful effects of ultraviolet rays, has an anti-xerophthalmic effect.

Betacarotene has an immunomodulating effect, apparently stimulating the differentiation of B- and T-lymphocytes.

Participates in the processes of regeneration of epithelial tissues and increases their resistance to infections.

PHARMACOKINETICS
Absorption at ingestion - fast and complete.

Metabolised in the liver with the formation of active forms of vitamin A, which bind to the retinol transport protein and are delivered to various organs and tissues.
In the presence of Zn 2+ in the liver, inactive products are formed.
It is excreted by the kidneys and with bile.

INDICATIONS
Prevention and treatment of vitamin A deficiency.

To increase nonspecific resistance of the organism under the influence of small radiation doses, X-ray examination, radiation and chemotherapy in oncology, laser therapy, immunodeficiency states, contact with pesticides.

Age-related macular degeneration.

As part of complex therapy: peptic ulcer of the stomach and duodenum, erosive gastritis, duodenitis, NNC, dysbacteriosis;
nonspecific diseases of the lungs and upper respiratory tract; wounds, burns, frostbites, trophic ulcers; polymorphic photodermatosis, vitiligo, local skin pigmentation, hyperpigmentation.
DOSING MODE
Apply inside and in the form of inhalation.
The dose is set individually, depending on the indications and the route of administration.
SIDE EFFECT
Possible: yellow coloration of the skin, constipation.

Rarely: arthralgia.

CONTRAINDICATIONS
Hypersensitivity to vitamin A.

PREGNANCY AND LACTATION
Betakarotene is used during pregnancy and lactation (breastfeeding) according to the indications.

SPECIAL INSTRUCTIONS
Betacarotene is used as a dye in the food industry.

DRUG INTERACTION
Calcium preparations, colestyramine, mineral oils, neomycin, tocopherol (vitamin E) reduce the absorption of betacaren.

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