Composition, form of production and packaging
? Drops for ingestion from a transparent to slightly cloudy liquid of a dark brown color; in the course of storage, a slight deposit may form.
100 ml
liquid extract of whole fresh Iberian plant bitter (1: 1.5-2.5) * 15 ml
liquid extract of dry roots of Angelica officinalis (1: 2.5-3.5) ** 10 ml
liquid extract of dried flowers of chamomile pharmacy (1: 2.0-4.0) ** 20 ml
liquid extract of dried fruits of caraway seeds (1: 2.5-3.5) ** 10 ml
liquid extract of dried fruits of milk thistle spotted (1: 2.5-3.5) ** 10 ml
liquid extract of dry lemon balm leaves (1: 2.5-3.5) ** 10 ml
liquid extract of dry leaves of peppermint (1: 2.5-3.5) ** 5 ml
liquid extract of dry herb celandine May (1: 2.5-3.5) ** 10 ml
liquid extract of dry licorice roots naked (1: 2.5-3.5) ** 10 ml
* Extractant: ethanol 50%.
** Extracting agent: ethanol 30%.
Excipients: ethanol - about 31% (volumetric ratio).
20 ml - bottles of dark glass with a dropper (1) - packs of cardboard.
50 ml - bottles of dark glass with a dropper (1) - packs of cardboard.
100 ml - bottles of dark glass with a dropper (1) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
Description of the drug approved by the manufacturer for the printed edition of 2017.
PHARMACHOLOGIC EFFECT
The drug has a pronounced anti-inflammatory effect, as well as normalizes the tone of the smooth muscles of the gastrointestinal tract: it helps to eliminate spasm without affecting normal peristalsis, and with reduced tone and motility has a toning, prokinetic effect. In an in vitro experiment inhibits the growth of six subspecies of Helicobacter pylori. Iberogast В® reduces the intensity of ulceration of the gastric mucosa, the secretion of hydrochloric acid, reduces the concentration of leukotrienes, enhances the production of mucins, increases the concentration of mucoprotein prostaglandin E 2 in the mucous membrane of the stomach.
PHARMACOKINETICS
Data on the pharmacokinetics of the drug are absent.
INDICATIONS
- for the treatment of functional disorders of the gastrointestinal tract (including irritable bowel syndrome), manifested by gravity in the epigastric region, gastric or intestinal spasms, belching, nausea, flatulence, constipation, diarrhea, or alternation;
- in the complex therapy of gastritis, peptic ulcer of the stomach and duodenum.
DOSING MODE
The drug is taken orally, 20 drops 3 times / day, before or during a meal, with a small amount of water.
The duration of therapy is 4 weeks.
An increase in the duration and conduct of repeated courses of treatment is possible on the recommendation of a doctor.
SIDE EFFECT
From the digestive system: nausea, vomiting, diarrhea.
Allergic reactions: skin manifestations, dyspnea.
If there are side effects, you must cancel the drug and consult a doctor.
CONTRAINDICATIONS
- Calculous cholecystitis;
- Children and adolescence under 18 years (due to inadequate clinical data);
- Hypersensitivity to the components of the drug.
With caution should prescribe the drug for liver disease, alcoholism, craniocerebral trauma, brain diseases - due to the content of ethanol in the drug.
PREGNANCY AND LACTATION
The drug should not be used during pregnancy and during breastfeeding.
APPLICATION FOR VIOLATIONS OF THE FUNCTION OF KIDNEYS
With caution: liver disease (due to the content of ethanol in the drug).
APPLICATION FOR CHILDREN
Contraindicated in children under the age of 18 due to inadequate clinical data.
SPECIAL INSTRUCTIONS
If the severity of the disease does not decrease within 14 days of the drug, or if there is a worsening of the symptoms, or if there are new complaints, the patient should consult a doctor.
The content of the ethanol preparation is from 29.5 to 32.6% (by volume). When you take 1 single dose (20 drops), the patient receives up to 0.24 grams of absolute ethyl alcohol. The maximum daily dose of the drug (60 drops) contains up to 0.72 g of absolute ethyl alcohol, which is lower than the ethanol content in 200 ml of apple juice or 75 ml of kefir.
Before use, the contents of the vial should be shaken.
During storage, slight turbidity or precipitation of a slight precipitate is possible, which does not affect the therapeutic efficacy of the drug.
Impact on the ability to drive vehicles and manage mechanisms
When using the drug, care should be taken when carrying out potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions (including vehicle management, working with moving mechanisms, dispatcher and operator work).
OVERDOSE
To date, no cases of drug overdose have been reported.
DRUG INTERACTION
Interaction with other drugs is currently unknown.
Consideration should be given to the possibility of interacting with drugs metabolized by the cytochrome P450 system (licorice roots, thistle fruits, chamomile flowers may have an inhibitory effect on a number of cytochrome P450 isoenzymes). At the same time, these effects are dose-dependent and are described when individual components are used at concentrations many times higher than the recommended doses of Iberogast В® .
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of reach of children, protected from light at a temperature of no higher than 25 В° C. Shelf life - 2 years.
