Universal reference book for medicines
Product name: DULKOLAX В® (DULCOLAX В® )

Active substance: bisacodyl

Type: Laxative drug that stimulates intestinal motility

Manufacturer: BOEHRINGER INGELHEIM INTERNATIONAL (Germany) manufactured by ISTITUTO de ANGELI (Italy)
Composition, form of production and packaging
Suppositories rectal white or slightly yellowish color, torpedo-shaped with a depression in the base, with a smooth or slightly oily surface.
1 supp.

bisacodyl 10 mg

Excipients: Witepsol W45 - 1690 mg.

6 pcs.
- strips of aluminum foil (1) - packs of cardboard.

Description of the drug approved by the manufacturer for the printed edition of 2011.


Bisacodyl is a locally acting laxative from the group of diphenylmethane derivatives.
As a local laxative with antiresorptive effect, Bisacodyl after hydrolysis in the large intestine increases the secretion of water and electrolytes in the large intestine, accelerates and increases its peristalsis. This leads to stimulation of defecation, a decrease in evacuation time and softening of the stool.
The effect is due to direct stimulation of nerve endings in the mucosa of the large intestine.


- constipation due to hypotension of the large intestine;

- cleansing of the intestine in terms of preoperative preparation;

- preparation for instrumental and roentgenological research.


For constipation, if the doctor did not appoint otherwise, it should be used: adults and children older than 10 years - 1 suppository per day.
The suppository is introduced into the rectum with a pointed end forward. The action takes about 30 minutes.
When preparing for research, pre- and post-operative treatment, medical conditions that require relief of defecation, Dulcolax should be used under medical supervision.

It is recommended in combination with tablets to achieve complete emptying.
In addition to the tablets taken the day before, one suppository is recommended in the morning.

From the digestive system: possible abdominal cramps, diarrhea.

Very rare reactions of hypersensitivity with cutaneous manifestations, extremely rarely reported the emergence of anaphylaxis.
The use of suppositories can be accompanied by pain and local irritation, especially with an anal fissure or ulceration proctitis.

- intestinal obstruction;

- obstructive bowel disease;

- Acute diseases of the abdominal cavity, including appendicitis;

- Acute inflammatory bowel diseases;

- severe abdominal pain associated with nausea and vomiting, which may be a sign of a more severe condition;

- severe dehydration;

- children under 10 years;

- Hypersensitivity to the drug or its components.


Data on reliable and well-controlled studies in pregnant women are not available.
Long-term experience of use has not revealed a negative effect of the drug on pregnancy. Bisacodyl does not penetrate into breast milk. However, as with other drugs, caution should be given to the drug during pregnancy, especially in I trimester, and during breastfeeding.

Contraindicated up to 10 years.

If constipation is not prescribed by the doctor, children over 10 years of age - 1 suppository per day.


Do not use the drug for a long time.
If there is a need for daily intake of laxatives, you should consult a doctor to determine such causes. Long-term use can lead to fluid loss, disruption of electrolyte balance and hypokalemia.
Dizziness and fainting were observed in patients taking Dulcolax.
The analysis showed that these cases are associated with fainting during defecation (or a syncope caused by stress during defecation) or with a vasovagal response to abdominal pain that may be associated with constipation, which forced patients to take laxatives and are not necessarily associated with taking the drug .
Children should not take bisacodyl without a doctor's recommendation.


When an overdose is possible: diarrhea, dehydration, cramps in the abdomen, violation of water-electrolyte balance, hypokalemia.
Dulcolax, like other laxatives, with a chronic overdose can lead to chronic diarrhea, abdominal pain, hypokalemia, secondary aldosteronism, urolithiasis. In connection with chronic abuse of laxatives, renal tubular damage, metabolic alkalosis and muscle weakness associated with hypokalemia can develop.
Treatment: symptomatic.


Diuretics or glucocorticosteroids increase the risk of electrolyte imbalance (hypokalemia) when taking high doses of Dulcolax.

Violation of the electrolyte balance (hypokalemia) enhances the action of cardiac glycosides.


The drug is approved for use as a means of OTC.


Store in a dry place at a temperature of no higher than 25 В° C.
Keep out of the reach of children. Shelf life - 5 years.
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