Universal reference book for medicines
Product name: DUTAN (DUTAN)

Active substance: mebeverine

Type: Myotropic antispasmodic

Manufacturer: ФП ОБОЛЕНСКОЕ (Russia)
Description of the active substance:
This information is a reference and it is not enough that the drug was prescribed by a doctor.
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PHARMACHOLOGIC EFFECT
Spasmolytic of myotropic action.
Reduces the tone and reduces the contractile activity of the smooth muscles of the digestive tract (mainly the large intestine).
PHARMACOKINETICS
When ingested, it undergoes pre-systemic hydrolysis and is not detected in the plasma.
Metabolised in the liver to veratric acid and mebeverin alcohol. Excreted mainly by the kidneys in the form of metabolites, in small amounts - bile (completely - within 24 hours).
INDICATIONS
Spastic conditions of the gastrointestinal tract caused by organic diseases.
Symptomatic treatment of pain, spastic conditions, unpleasant sensations in irritable bowel syndrome.
DOSING MODE
Take inside 100 mg 4 times or 135 mg 3 times / day.
When the desired clinical effect is achieved, the dose is gradually reduced within a few weeks.
SIDE EFFECT
Possible: nausea, allergic reactions, dizziness, headache, diarrhea, constipation.

CONTRAINDICATIONS
Pregnancy, hypersensitivity to mebeverine.

PREGNANCY AND LACTATION
Mebeverin is contraindicated for use in pregnancy.

SPECIAL INSTRUCTIONS
Impact on the ability to drive vehicles and manage mechanisms

During the treatment period it is necessary to refrain from driving motor vehicles and practicing potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

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