Composition, form of production and packaging
? Capsules soft gelatinous, oval; the contents of the capsules are an oily liquid of yellow color, odorless.
RRR -? - tocopheryl acetate concentrate 182 mg,
in t.ch. RRR -? - tocopheryl acetate 147 mg (200 IU)
soybean oil 35 mg
Auxiliary substances: soybean oil (88 mg).
Capsule shell composition: gelatin, glycerol, sorbitol 70% solution (non-crystallisable), purified water.
20 pcs. - blisters (3) - packs of cardboard.
20 pcs. - blisters (5) - packs of cardboard.
INSTRUCTION FOR THE SPECIALIST.
The product description was approved by the manufacturer for the 2009 print edition.
Vegetable vitamin E. Has an antioxidant effect. Protects the cellular membranes of body tissues from oxidative changes. Stimulates the synthesis of heme and heme-containing enzymes - hemoglobin, myoglobin, cytochromes, catalase, peroxidase. It inhibits the oxidation of unsaturated fatty acids. Inhibits the synthesis of cholesterol, promotes the normalization of lipid levels in blood plasma, prevents increased permeability of capillaries. Reduces clotting of blood, participates in tissue respiration and other processes of tissue metabolism.
Vitamin E is necessary for the normal development and functioning of the gonads. Participates in the biosynthesis of collagen, heme and proteins, activates cell proliferation.
Data on the pharmacokinetics of the drug Doppelgerc Vitamin E forte are not available.
- hypovitaminosis E;
- increased physical and mental loads;
- in the complex therapy of peri- and postmenopausal disorders;
- degenerative and proliferative changes in the joints, ligamentous apparatus of the spine, muscles;
- asthenic conditions (including in old age).
Adults appoint 1 capsule / day, after eating. The capsule is taken orally, without chewing, with a small amount of liquid.
With degenerative and proliferative changes in the joints, ligamentous apparatus of the spine, muscles - 1 capsule / day.
With hypovitaminosis E - 1 capsule / day, the maximum dose - 2 capsules / day. The duration of treatment is determined by the attending physician.
Allergic reactions: itching, skin hyperemia.
acute myocardial infarction;
- children's age till 18 years;
- Hypersensitivity to the components of the drug.
With caution should prescribe the drug in severe cardiosclerosis (after a previous myocardial infarction), with an increased risk of thromboembolism, hypoprothrombinemia caused by vitamin K deficiency.
PREGNANCY AND LACTATION
During pregnancy and during breastfeeding, the drug is prescribed in an average daily dose for adults under the supervision of a doctor.
It is necessary to strictly follow the dosing regimen.
With long-term use of the drug and / or the need to prescribe repeated courses of therapy, it is recommended to periodically monitor blood coagulation indicators, as well as the level of cholesterol in the blood.
Symptoms: when taking vitamin E for a long period in doses of 400-800 IU / day, blurred vision, dizziness, headache, nausea, severe fatigue, diarrhea, gastralgia, asthenia.
When taking a dose of more than 800 IU / day for a long period - an increased risk of bleeding in patients with hypovitaminosis K, a disorder of thyroid hormone metabolism, a sexual function disorder, thrombophlebitis, thromboembolism, necrotic colitis, sepsis, renal failure, bleeding in the retina, hemorrhagic stroke, ascites.
Treatment: cancellation of the drug. Conduct symptomatic therapy, appoint GCS.
Iron preparations are recommended to be used 8-12 h before or after taking the drug Doppellerts Vitamin E forte (because iron absorption is possible).
The intake of vitamin E in high doses can increase the effect of indirect anticoagulants. With simultaneous reception of indirect anticoagulants and vitamin E, it is necessary to regularly monitor blood coagulability.
Enhances the effect of GCS, NSAIDs, antioxidants.
Vitamin E in high doses can cause vitamin A deficiency in the body.
Increases the effectiveness of antiepileptic drugs in patients with epilepsy (who have increased blood levels of products of lipid peroxidation).
Colestramine, colestipol, mineral oils reduce the absorption of vitamin E.
TERMS OF RELEASE FROM PHARMACY
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored out of reach of children at a temperature of no higher than 25 В° C. Shelf life - 4 years.