Universal reference book for medicines
The name of the preparation: VACCINE KU-FEVER M-44 LIVING (Q FEVER VACCINE M-44 LIVE)

Active substance: nonappropriate

Type: Vaccine for the prevention of Ku fever

Producer: NGO MIKROGEN (Russia)
Composition, form of production and packaging
Lyophilizate for the preparation of a suspension for cutaneous scarification
in the form of an amorphous mass, which is a pink tablet with a grayish, yellowish or brownish hue.

1 amp.

a live culture of Burnett's coxiella of strain M-44 vaccine grown in yolk sacs of developing chick embryos 10 doses

1 inoculation dose (0.05 ml) contains from 5x10 7 to 5x10 9 minimal infectious doses (MIDe) of Bernet's coke for chick embryos

Components of the drying medium: sucrose 1%, milk pasteurized 49%.

Solvent: sodium chloride injection for 0.9%.

10 doses - ampoules (5) complete with a solvent of 5 ml amp.
5 pieces. - packs cardboard.

Description of the drug approved by the manufacturer for the printed edition of 2014.


A single injection of the vaccine is accompanied by the development of specific immunity 3-4 weeks after vaccination.


Specific prophylaxis of Ku fever is carried out at the age of 14 years.

Contingents subject to vaccination:

- persons performing work for the preparation, storage, processing of raw materials and livestock products obtained from farms where diseases of Ku-fever cattle are registered;

- persons performing work on harvesting, storage and processing of agricultural products in the enzootic territories according to Ku-fever;

- persons working with live cultures of pathogens of Ku-fever.


The vaccine is given once by the skin method of scarification at a dose of 0.05 ml.
Revaccination is carried out at a dose of 0.05 ml not earlier than 1 year after the initial vaccination to persons whose serum lacks specific complement-binding antibodies.
In the ampoule with the vaccine, 0.5 ml of sodium chloride solution for injection, 0.9%, immediately before vaccination.
The vaccine should dissolve within 2 minutes to form a thick, homogeneous suspension of pink color with a grayish, yellowish or brownish hue.
The place of grafting (the outer surface of the middle third of the shoulder) is treated with 70% alcohol or ether solution (the use of other disinfectant solutions is not allowed).
After their evaporation, 2 drops of diluted vaccine are applied at a distance of 30-40 mm through an eye dropper or syringe through a needle. Sterile scarifier, through each drop of vaccine applied to the skin, three cross-shaped incisions of 8-10 mm in length are made 3-4 mm apart so that the blood appears through small "dewdrops". The flat side of the scarifier is rubbed into the incision vaccine, after which the vaccine should dry for 5-10 minutes. The subsequent processing of the site is not carried out.
The dissolved vaccine is usable for 30 minutes when stored under a sterile tissue at room temperature and for 60 minutes when stored at a temperature of 2 to 10 ° C.

The introduction of the drug is recorded in the prescribed registration forms with an indication of the date of administration, dose, manufacturer, serial number, response to vaccination.


The general reaction to vaccination develops on day 2-3 in individual vaccinated individuals and is expressed in a one-day malaise, chills, headache and an increase in temperature to 37.5 ° C.

Local reaction, characterized by reddening and nodular swelling along the incision, usually develops not less than 90% of the vaccinated.
The duration of the local reaction is 3-4 days.

- acute infectious and non-infectious diseases;
chronic diseases in the acute stage; Inoculations are carried out not earlier than a month from the moment of recovery or remission;
- allergic diseases (according to anamnesis): bronchial asthma, atopic dermatitis, pollinosis, etc .;
an allergy to a chicken egg;
- chronic diseases of the upper respiratory tract and lungs;

- systemic connective tissue diseases;

- immunodeficiency states (primary and secondary);

- pregnancy and lactation;

- malignant diseases.

The possibility of vaccinating people suffering from diseases not listed in this list of contraindications is determined by the doctor, based on the health status of the vaccinated person.

Immediately before vaccination, the doctor conducts a thorough medical examination with thermometry and a survey of vaccinees to identify contraindications.
At a temperature above 37 ° C vaccinations are not carried out.

Application during pregnancy and during lactation is contraindicated.


Precautions for use

Before use, every ampoule with the vaccine is carefully scanned.
Unsuitable for use in the presence of cracks in the ampoule, foreign inclusions, unusual coloring vaccine and other defects, as well as broken markings and expired shelf life.
Special precautions for the destruction of unused medicinal product

Unused vaccine, as well as rejected ampoules are opened and rendered harmless by immersion in disinfectant solutions (chloramine solution 3% or sodium hydroxide solution 3%, or hydrogen peroxide solution 6%, or biodester extra solution 1% for 1 day) and boiling for 1 hour.

Information about the possible effect of the drug on the ability to drive vehicles, mechanisms.

No information.


Not installed.


Vaccinations are carried out not earlier than 1 month after the previous immunization with other vaccines.
Simultaneous inoculations with vaccines against Ku-fever and brucellosis are allowed. Brucellosis vaccine is administered in accordance with the instructions for use of the drug in the other arm.

For treatment and preventive and sanitary facilities.


Store and transport in accordance with SP at a temperature of 2 ° to 8 ° C.
Freezing is not allowed.
Keep out of the reach of children.
Shelf life 2 years.
Alphabetical index of medicines:
A  B  V  G  D  E  J
Z  I  Y  K  L  M  N
O  P  R  S  T  U  F
H  C  CH  SH  E  U  Y
Privacy policy:
Copyright 2009 - 2017. Universal reference book of medicines. All rights reserved.
When using site materials, an active hyperlink is required!