Universal reference book for medicines
Product name: BYSTRUMGEL ® (BYSTRUMGEL)

Active substance: ketoprofen

Type: NSAID for external use

Manufacturer: Chemical-Pharmaceutical Plant Akrihin (Russia)
Composition, form of production and packaging
?
Gel for external use 2.5% colorless, almost transparent, with a specific odor; opalescence is allowed.
1 g

ketoprofen 25 mg

Auxiliary substances: ethanol (ethyl alcohol) rectified, nipagin, carbomer, trometamol, lavender oil, neolium oil, purified water.

30 g - tubes (1) - packs of cardboard.

50 g - tubes (1) - packs of cardboard.

100 g - tubes (1) - packs of cardboard.

INSTRUCTION FOR THE SPECIALIST.

Description of the drug approved by the manufacturer for the printed edition of 2016.

PHARMACHOLOGIC EFFECT

NSAID, a derivative of propionic acid.
Has analgesic, anti-inflammatory effect.
Inhibiting COX-1 and COX-2, inhibits the synthesis of prostaglandins.
It has anti-bradykinin activity, stabilizes lysosomal membranes. Reduces the secretion of cytokines, inhibits the activity of neutrophils.
With articular syndrome, it alleviates pain in joints at rest and during movement, reduces morning stiffness and swelling of the joints, contributes to an increase in the volume of movements.

PHARMACOKINETICS

Suction

With external application of the gel, extremely slow transdermal absorption of ketoprofen takes place, which ensures the maintenance of its concentration in inflamed tissues within the therapeutic level for a long time.
Absorption into the systemic circulation is negligible. Practically does not cumulate. Bioavailability of the gel is about 5%.
Distribution

Ketoprofen penetrates well into the synovial fluid and connective tissue.

INDICATIONS

Inflammatory or traumatic lesions of joints, tendons, ligaments and muscles:

- arthritis, periarthritis;

- tendonitis, tendosinovitis;

- bursitis;

- bruises, ligament injuries, dislocations, damage to the knee meniscus;

- torticollis;

- Lumbago.

Phlebitis, periphlebitis.

DOSING MODE

The drug is applied to the skin of the painful area 2 times / day, squeezing from the tube about 3-5 cm of gel or more (depending on the area of ​​the painful area), distribute a uniform thin layer and gently rub until completely absorbed.

In order to increase the effectiveness of therapy, it is possible to apply the gel under a dry occlusive dressing.

SIDE EFFECT

In isolated cases: allergic reactions that require drug withdrawal, photosensitivity.

CONTRAINDICATIONS

- dermatoses;

- eczema;

- infected abrasions and wounds;

- Pregnancy;

- lactation period;

- childhood;

- Hypersensitivity to ketoprofen or other components of the drug.

PREGNANCY AND LACTATION

The drug is contraindicated for use in pregnancy and lactation.

APPLICATION FOR CHILDREN

Contraindication: children's age.

SPECIAL INSTRUCTIONS

Do not apply gel to open wounds or damaged skin.

Do not let the gel get on the mucous membranes and eyes.

OVERDOSE

Cases of overdose with the use of the drug Bystrumgel ® is not described.

DRUG INTERACTION

At present, no cases of drug interaction between the drug Bystrumgel ® and other medications have been identified.

TERMS OF RELEASE FROM PHARMACY

The drug is approved for use as a means of OTC.

TERMS AND CONDITIONS OF STORAGE

The drug should be stored in a dry, protected from light, out of reach of children at a temperature of 15 ° to 25 ° C.
Shelf life - 2 years.
Alphabetical index of medicines:
A  B  V  G  D  E  J
Z  I  Y  K  L  M  N
O  P  R  S  T  U  F
H  C  CH  SH  E  U  Y
Privacy policy:
Copyright 2009 - 2017. Universal reference book of medicines. All rights reserved.
When using site materials, an active hyperlink is required!