Universal reference book for medicines
Product name: ADAPTOL (ADAPTOL)

Active substance: nonappropriate

Type: Tranquilizer (anxiolytic)

Manufacturer: OLAINFARM (Latvia)
Composition, form of production and packaging

Tablets are white or almost white, round, flat-cylindrical, with a facet and a risk.

1 tab.

tetramethyltetraazabicyclooctanedione 500 mg

Excipients: methylcellulose - 3.3 mg, calcium stearate - 1.7 mg.

10 pieces.
- packings cellular planimetric (2) - packs cardboard.

Description of the drug approved by the manufacturer for the printed edition of 2017.


Anxiolytic (tranquilizer).
Adaptol is close in chemical structure to the natural metabolites of the body - its molecule consists of two methylated fragments of urea, composition of a bicyclic structure.
Adaptol acts on the activity of the structures entering the limbic-reticular complex, in particular, on the emotionogenic zones of the hypothalamus, and also affects all the four main neurotransmitter systems: GABA-, choline-, serotonin- and adrenergic, promoting their balance and integration, but has no peripheral adrenoblocking effect.

Eliminates or reduces anxiety, anxiety, fear, inner emotional tension and irritability.
Soothing effect is not accompanied by muscle relaxation and violation of coordination of movements.
It does not reduce mental and motor activity, therefore Adaptol can be used during a working day or school.
Does not create an upbeat mood, a sense of euphoria.
Sleeping effect does not have, but enhances the effect of hypnotics and improves sleep during its violations.

Adaptol facilitates or removes nicotine abstinence.

In addition to soothing, nootropic effect.
Adaptol improves cognitive functions, attention and mental performance, without stimulating the symptoms of productive psychopathological disorders - nonsense, pathological emotional activity.


After oral administration, Adaptol is well absorbed from the digestive tract (77-80%).
C max of the active substance in the blood plasma is reached after 0.5 h after administration of the drug. The high concentration of the active substance persists for 3-4 hours, then gradually decreases.

Up to 40% of the dose is associated with erythrocytes.
The remainder does not bind to plasma proteins and is in the blood plasma in a free form, so the active substance is unimpeded throughout the body and freely crosses the cell membranes.

The active substance is not metabolized and does not accumulate in the body.


About 55-70% of the accepted dose is excreted from the body with urine, the rest - with feces in unchanged form during the day.


- neuroses and neurosis-like conditions (irritability, emotional instability, anxiety and fear);

- to improve portability
neuroleptics and tranquilizers to eliminate the associated somatovegetative and neurological side effects;
- cardialgia of various genesis (not associated with ischemic heart disease);

- nicotine abstinence (as part of complex therapy as a means of reducing the craving for tobacco smoking).


The drug should be taken inside regardless of food intake, 500 mg 2-3 times / day.
The maximum single dose is 3 g, the daily - 10 g. The duration of the course of treatment is from several days to 2-3 months.
In complex therapy, as a means of reducing the craving for tobacco smoking , 500-1000 mg 3 times / day are prescribed for 5-6 weeks.


Rarely: dizziness, lowering of blood pressure, dyspeptic disorders, allergic reactions (skin rash, itching).

When used in high doses: bronchospasm, lower body temperature, weakness.


- Pregnancy;

- the period of lactation (breastfeeding);

- children and adolescence under 18;

- Hypersensitivity to the components of the drug.


Contraindicated use of the drug during pregnancy and lactation (breastfeeding).


Contraindicated in children and adolescents under 18 years.


With lowering blood pressure and / or body temperature (possibly at 1-1.5 В° C), taking the drug is not necessary.
AD and body temperature are normalized independently.
When allergic reactions occur, the drug should be discontinued.

Addiction, addiction (mental and physical) and withdrawal syndrome with the use of the drug Adaptol
not installed.
Impact on the ability to drive vehicles and manage mechanisms

The drug is able to cause a decrease in blood pressure and weakness, which can adversely affect the ability to drive vehicles and work with mechanisms.
Care should be taken when using in patients who engage in potentially hazardous activities.

The drug is low toxicity.
A typical clinical picture of an overdose is missing. Serious poisoning is not registered.
Symptoms: weakness, arterial hypotension, dizziness are possible.

Treatment: if suspected of overdosage, gastric lavage, symptomatic therapy should be performed.


Possible simultaneous use of Adaptol with neuroleptics, tranquilizers (including benzodiazepines), hypnotics, antidepressants and

The drug is released by prescription.


The drug should be stored out of reach of children, dry place, at a temperature of no higher than 25 В° C.
Shelf life - 4 years.

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