Vinorelbin (vinorelbine)


VINORELBIN (Vinorelbine).
     3? , 4? - Didegidro-4? - dezoksi-8? - norvinkaleykoblastin.
     Synonym : Navelbin, Navelbine.
     Belo yellow or light brown amorphous powder. Mg in the water.
     Semi derived alkaloid extracted from plants pink Periwinkle (Vinca rosea L.).
     Available in the form of tartrate.
     The structure and action close to vinblastinu and vincristine.
     Applied with cancer lung (except melkokletochnogo), breast and ovarian.
     Enter intravenous (about 15-20 minutes). Regular dose (with monotherapies) 25-30 mg / m 2 1 day a week.
     Let's ex tempore in 125 ml isotonic solution (0.9%) sodium chloride.
     Possible side effects and contraindications are basically the same as that vinblastina and vincristine.
     The solution should be wary of falling into surrounding tissue (necrosis opportunity). Haematological must be carefully monitored.
     Product : 1% solution in vials of 1 and 5 ml.
     Storage : List B.

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