Troventol (troventolum)
TROVENTOL (Troventolum).
Tropinovy broadcast d, 1-(2-phenyl gidroksimetil-2-) oil yodmetilat acid.
Synonym: Truvent.
White or white with little yellowish tinge crystalline powder. Few soluble in water.
According to the chemical structure similar to atropine, but, like atroventu a quaternary ammonium derivative. Unlike molecules atropine troventola molecule contains additional methyl group when nitrogen atom tropanovogo cycle, as well as etilnuyu group eterifitsiruyuschey acid balance.
Is antiholinergicheskim substances, acting mainly on M-holinoretseptory. Compared with the effects of atropine on troventola holinoretseptory Muscle bronchus stronger and lasting less pronounced impact on holinoretseptory other organs (heart, bowel, salivary glands). As quaternary compounds ammonievoe troventol not penetrate through cross the blood-brain barrier. Election of troventola gives it advantages compared with atropine as bronhorasshiryayuschego funds and better portability.
Troventol very active bronholiticheskoe funds used for chronic obstructive bronchitis, bronhiolospazme with chronic pneumonia, bronchial asthma attacks light and medium gravity, with bronhiolospazme associated with flu infections (including patients older).
As atrovent (Ipratropium bromide), troventol most effective when bronhiolospazmah caused hyperactivity holinergicheskoy system when adrenomimetiki (see Ortsiprenalin) and metilksantiny (see Theophylline) inadequate.
There are references to the possibility of troventola to diagnose hidden bronhospasticheskogo syndrome.
Apply trovental of inhalations of aerosol containers. There are two cylinders with dosage: 12, 5 and 25 mg in the container. When you click on one cylinder valve with a 12, 5 mg single dose given troventola 40 µ g (0.04 mg), but when you click on the cylinder valve with 25 mL of 80 µ g (0.08 mg).
Preventive and curative dose of a drug may vary from different patients from 40 to 160 ug. Daily dose is about 120 and 480 ug.
Beginning with the appointment of 40 µ g, that is a breath when you click on the valve Ballina 12, 5 mg. With little effect produced two breath (two hits), a single dose increased to 80 ug. В зависимости от клинического эффекта и переносимости препарата увеличивают разовую дозу до 80 160 мкг, при этом для удобства пользуются баллоном с 25 мг атровента (1 - 2 нажатия). With sufficient effect of occasional dose of 40 µ g continue to enjoy the container with 12, 5 mg troventola.
Aerosol Inhalation repeated every 4 to 6 hours
To correct use of aerosol container remove the protective cap with klapanno- spray heads, and 2 to 3 times vstryahivayut cylinder; Make a deep breath; Have klapanno- raslylitelnoy cylinder head down, cover it snaffle lips while clicking on the bottom and the cylinder head (it is accompanied by release single-dose aerosol) make possible a deep breath, followed by delays breathing for a few seconds.
After inhalation wear protective cap on klapanno- spray head.
Inhalation troventola generally well tolerated, but at the holinoliticheskim of possible drought in the mouth, throat MEDOSIL in light violations accommodation. If necessary, in these cases, reduce or increase the dose intervals between inhalation and highly expressed in side events temporarily cease inhalation.
Troventol contraindications with glaucoma and pregnancy.
You can combine with other troventol bronhorasshiryayuschimi means (see adrenomimetikami - Ortsiprenalin and others derivative ksantina-see Theophylline, stimulation).
Form of: aluminum aerosol containers (Ae r s lum on T roventoli) with a capacity of 21 grams, containing troventola 12, 5 or 25 mg. Each container contains 300 single doses. Clicking on the metering valve cylinder allocated aerosol containing 40 µ g (0.04 mg), or 80 µ g (0.08 mg) troventola.
Storage: List A. sheltered from the effects of heat and direct sunlight place at a temperature no higher than 30 C.
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Materials allowed to copy only with the active hyperlink to the handbook of medicines
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