TRIOMBRAST 60% and 76% FOR INJECTION (Triombrastum 60% et 76% pro injectionibus).

     Triombrast (acid) is triyodsoderzhaschim drug.

     Triombrast injection is aqueous solutions containing mixtures, and sodium salts metilglyukaminovoy triombrasta (3, 5-diatsetilamino-2, 4, 6 triyodbenzoynoy acid) in the ratio of 1:6, 6. Similar foreign drugs produced under the title: Verografin, Urografin, Urotrast.

     Sodium salt of 3, 5 diatsetilamino -2, 4, 6-triyodbenzoynoy acid previously issued as a means rengenokontrastnogo called triombrin. "

     Metilglyukaminovaya salt of the acid produced abroad called Perografin. "

     A transparent colorless or light yellow liquid; PH 6, 5, 7, 7; 1 ml 60% solution contains 292 mg of iodine, 1 mL of 76% solution of iodine - 370 mg.

     Apply for X-ray studies of blood vessels and the heart (angiocardiography; Aortography, arteriography, selective angiography and others), kidney, urinary tract.

     The product is derived from the body quickly kidneys.

     Depending on the type of evidence triombrast intravenously or in cavities (in the urinary bladder, kidney lohanki).

     To explore the use of the drug sensitivity of the individual patient to iodine, which the eve of introducing veins (very slowly) triombrast up to 1 ml (based on the patient's age). In the case of high sensitivity (the emergence itching; Rash, runny nose, severe, general malaise, tachycardia, a violation breathing, cyanosis, etc.) of the drug counter.

     In angiokardiografii applied to 60 ml 76% solution triombrasta (type 10 to 30 ml per second); When aortografii give aortu 30-60% 76 ml solution of the drug (10 to 30 mL / s); When peripheral arteriografii the upper limbs impose vnutriarterialno 60% solution of the drug in the number of 10-20 ml, at the lower limbs-20-40 ml (8 - 12 ml / s); when flebografii used intravenously at the top limb 10-20% 60 ml solution triombrasta, at the lower limbs-20 40 ml (3 - 5 mL / s); when splenoportografii introducing spleen Z0-50 mL of 76% solution of the drug (8 mL / s).

     In the study ways to apply for urinary excretory urografii 20 ml 60% triombrasta (0.3 mL / s); Sometimes impose intravenously adults 40-60 mL of 60% or 76% solution (0.3 mL / s).

     To kind urografii give veins mixture of 80 mL of 60% and 76% solutions triombrasta with 80 ml of 5% glucose solution (20 to 30 drops per minute).

     For retrogradnoy pielografii and tsistografii razvodyat triombrast isotonic sodium chloride solution, or 5% glucose solution to the 30% solution. For pielografii imposed solution (typically 3 to 8 mL) through the urinary catheter in the way of low pressure radiological under visual control; Tsistografii to give urinary bladder 100-200 ml.

     With triombrasta can sense heat, dizziness, nausea, vomiting, increasing pulse, cyanosis. In some cases increased, the sensitivity, not identified in the preliminary study may develop rash, swelling Kvinke, astmatoidnogo attack anafilaktoidnyh reaction until anafilakticheskogo shock and other side effects.

     It should be borne in mind that the high degree of sensitivity to triombrastu or overdose possible arrhythmia, ventricular fibrillation, cardiac arrest.

     With the drug in blood vessels may develop in the future flebita, thrombosis.

     Contraindications to the spine and vydelitelnoy urografii with triombrastom are Idiosyncrasy drug iodine, hypertonia, heavy damage to the liver and kidney parenchyma, active tuberculosis, myocardial damage, severe stage of hypertensive disease, the state of shock, collapse, a significant increase in the index protrombina blood and collapse, the total heavy state sick. Contra phlebography in acute forms flebita.

     Since the introduction of blood triombrasta track is increased pressure on the heart, its use in patients with congestive heart failure, coronary blood violation, as well as after a heart attack recently carried Chavez should be taken with great caution (on life testimony).

     Please heightened sensitivity to impose triombrasta from those prone to allergic reactions. As sick for several days before the drug appoint protivogistaminnye funds.

     Form release: 60% and 76% triombrast injection of 20 ml ampoule.

     Storage: in sheltered from the world scene.

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