Triyodtironina hydrochloride (triiodthyronini hydrochloridum)


TRIYODTIRONINA HYDROCHLORIDE (Triiodthyronini hydrochloridum) *.
     Synthetic drugs, related to construction and operation of natural thyroid hormone (see Tireoidin); The form hydrochloride.
     Synonyms: Liotironin, Lyothyronin, Liothyronine, Liothyroninum, Trionine and others.
     Indications for use are the same as for tireoidina. Triiodothyronine faster and better absorbed than tireoidin has a more rapid effect, since hypothyroidism processes Intake usually violated application triyodtironina particularly useful in the first stage of treatment. The initial manifestations of the drug with hypothyroidism have through 4 - 8 hours He often performs with resistance tireoidinu not cause allergic reactions. Especially shows Triiodothyronine in miksedematoznoy coma.
     Assign inside 1 - 3 times a day. Doses individualiziruyut in accordance with the age of patients, and during the illness. The product can be used in conjunction with tireoidinom. When tireoidina triyodtironinom come estimated that 20 to 40 µ g (0.02 - 0.04 mg) triyodtironina with 0.1 g tireoidina.
     Adults appointed from 5 to 25 ug per day. If necessary, gradually increasing the dose to 40-60 µ g, sometimes up to 100 µ g (0.1 mg) a day (in the hospital to 150 µ g / day).
     For treatment miksedematoznoy coma (without surgery violations) designate 100 µ g 2 times a day, then reduce the dose.
     In eutireoidnom endemic goitre or sporadic goitre, as well as limfomatoznom tireoidite (goitre Hashimoto) worth adding to receive tireoidina Triiodothyronine dose of 10 to 20 ug.
     In the diffuse toxic goitre Triiodothyronine apply after enduring remission in doses not exceeding 20 µ g, combined with antitireoidnymi drugs.
     Children with hypothyroidism and miksedeme useful in the treatment tireoidinom add 5 to 10 ug triyodtironina.
     Treatment triyodtiraninom, especially in overdose can lead to the same complications as the application tireoidina.
     In applying triyodtironina coronary atherosclerosis in patients need special care, as well as possible attacks stenocardia; The initial dose should be no more than 5 to 10 µ g / day; Gradual improvement is permissible only under the supervision of electrocardiograms. In miksedematoznoy coma in patients with coronary irregularities dose should not exceed 10 to 12 µ g 2 times a day.
     Caution is necessary in the treatment of patients with secondary hypothyroidism lack crust ? (possibly growing phenomenon gipokortitsizma development addisonicheskogo Stroke).
     Contraindications are the same as for tireoidina.
     Form release: pills on 20 and 50 ug.
     Storage: List B. In a cool, sheltered from the world scene.
     Manufactured in Germany Tireokomb product (Thyreocomb) in one tablet contains 0.01 mg triyodtironina; 0.07 mg L-tiroksina and 0.15 mg of potassium iodide.
     Indications for use are the same as for tireoidina and triyodtironina. Assign inside averaging 1 / 2 to 2 pills a day.
     Tireotom (Thyreotom) contains Triiodothyronine in combination with L-tiroksinom.

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