Trifluperidol (trifluperidolum)


TRIFLUPERIDOL (Trifluperidolum). 4 - (meta Triftormetilfenil) -1 [3 `- (para-ftorbenzoil) - propyl] piperidinol- 4, or 4-[4 - (meta triftormetilfenil) - 4-oksipiperidino] 4'- ftorbutirofenon.
     Synonyms: Trisedal, Flumoperonum, Psicoperidol, Trifluperidol, Triperidol, Trisedyl.
     For construction and operation close to galoperidolu. It features a group of CF 3, in the meta position fenilnogo kernels (from PIPERIDINE) instead of chlorine atom in the parameters of a galoperidola.
     He has a strong adjunct activity. Increases of rape, drugs, analgesics. Provides protivosudorozhnoe and strong protivorvotnoe effect. He has a strong katalepticheskoy activity. There has holinoliticheskogo actions; Strong central dofaminovye blocks receptors.
     Trifluperidol antipsychotic is a powerful tool. He quickly redutsiruet gallyutsinatorno- nothing agitation. On Manic ability pain stimulation than other adjunct.
     Apply with psychosis involving motor and mental stimulation, especially for kupirovaniya katatonicheskogo and gebafrennogo excitation; With prolonged attacks periodically schizophrenia; When state, accompanied by severe depression and crazy; When alcoholic psychosis. In some cases, the lack of effective actions in other brain. It may also be a means protivorvotnogo.
     Assign inside and intramuscularly.
     Inside used since -0,0005 dose of 0.00025 grams (0.25 - 0.5 mg) a day, and then, depending on the effect and increase the portability dose of 0.25 - 0.5 mg every 2 to 3 days . Daily dose is usually 2 to 6 mg (up to 8 mg). Assign 2 - 4 reception after the meal.
     Children under age 5 appoint 1 / 4, and 5-15 -1 / 2 adult dose.
     In chronic vnutrimyshechnogo beginning with the introduction of 1, 25, 2, 5 mg, and then gradually replace drug injection reception inside.
     For kupirovaniya acute delusional state impose intramuscularly 1, Feb. 25, 5 mg (sometimes up to 5 mg) once or repeated (in the form of short courses).
     Possible complications and contraindications basically the same as when applying galoperidola.
     Method of issuance: pills to 0.0005 g (0.5 mg); 0.1% solution for the reception inside in vials of 10 ml (1 ml contains 1 mg drug); 0.25% solution of 1 ml ampoule.
     Storage: List B.

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