TRIAMTEREN (Triamterenum). 2, 4, 7-Triamino-6- fenilpteridin7

     Synonyms: Pterofen, Amteren, Diutac, Diuteren, Dyren, Dyrenium, Dytac, Fluxinar, Jatropur, Neuuron, Noridyl, Pterofen, Reviten, Taturil, Teridin, Triamterene, Triarene, Trispan, Triteren, Triurene, Urocaudal and others.

     Triamteren reduces the permeability of cell membranes for ion channel distal sodium and increased their allocation from the urine without increasing the allocation of potassium ions. Secretion of potassium ions in the distal Channel decreases. The product can reduce gipokaliemiyu caused benzotiadiazina derivatives, and enhance diuretichesky effect last.

     The product is rapidly absorbed; Diureticheskoe action after receiving inside a 15-by 20 minutes, the maximum effect through 2 to 3 h after administration and restrained for a period of 12 h.

     Apply with infections caused by circulatory failure, liver cirrhosis, nefroticheskim syndrome. In connection with the actions kaliysberegayuschim particularly shown for the combined application with tiazidnymi diuretikami, as well as in patients with liver problems digitalis glycosides, which is based on fiber.

     Assign inside, alone and in combination with other diuretikami. In a separate application for the 0.05-0.1 0.2 grams a day (1 - 2-admission after breakfast and lunch), in combination therapy, smaller doses (eg, 0,025 grams triamterena and 0.0125 g dihlotiazida). Gradually increase the dose (to avoid too fast or profuznogo diureza).

     Usually taking the drug daily.

     When you receive triamterena may, in some cases, nausea, vomiting, headache, down AD.

     Alkaloza, disorders, delayed uric acid, no, but can giperkaliemiya. In a lengthy application may increase of urea in the blood. In these cases, not to take drugs every day, a day and a smaller dose, alternating hosting benzotiadiazina diuretics group. Some patients in the application triamterena developed hyperglycemia and giperurikemiya.

     Form release: capsules of 0.05 g (50 mg) drugs.

     Storage: List B.

     Under the title "Triampur kompozitum" (T riampur with mpositum) in Germany issued tablets containing 25 mg triamterena and 12, 5 mg digidrohlortiazida (dihlotiazida). Assign with heart, kidney infections, astsite, liver cancer, etc.

     Is usually outpatients and 1 tablet two times a day (morning and afternoon after eating), in-patient-2 tablets two times a day.

     Form release: tablets in a package of 50 pieces.

     A similar domestic product is called Triamtezid "(T riamtezidum).

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