Trazodone (trazodonum)
TRAZODON (Trazodonum) *. 2 - (3-[4 - (3-Hlorfenil) -1 - piperazinil] - propil-) 1, 2, 4-triazolo- [4, 3-a] - piridin-3- (2 H) - ON.
Synonyms: Azona, Beneficat, Bimaran, Desyrel, Geripax, Menegan, Molipaxin, Pragmarel, Pragmazine, Sideril, Thombran, Tramensan, Trazolan, Trazone, Tresin, Trittico.
The product provides antidepressant (timolepticheskoe) action, combined with anksioliticheskim and trankviliziruyuschim effect. By pharmacological properties and actions neyrohimicheskomu different from the typical antidepressants; Diminish the impact of the depressed rezerpina weakens the central and peripheral effects fenamina noradrenalina effect; Not having a noticeable impact on neyronalny taking rest, but selectively block the takeover serotonin.
Apply in different forms depressions (endogenous, psihoticheskie, nervous, somatogennye and others) with anxiety, tension.
Due to the lack of good portability holinoliticheskogo of Trazodone widely used in the treatment of elderly patients with organic disease agent, as well as in complex treatment of patients with somatic disease, complicated by mental disorders (anxiety, tension, etc.).
Assign inside, and sometimes intramuscularly in the veins. Initial dose admission inside of 50 mg three times a day, and then, depending on the type and severity of depression and 300-500 mg per day. Therapeutic effect usually seen through 3 - 7 days from the start of treatment.
When applying as a means anksioliticheskogo (with somatic disorders and depression) designate to 25 mg three times a day.
In veins and intramuscularly give dose of 50 mg as anksioliticheskogo for sedation of operational intervention.
Adverse events: fever, rash, headache, dizziness, insomnia, lower blood pressure, were relatively rare and are combined with a decrease in dose. The product should not be appointed concurrently with MAO inhibitors.
Method of issuance: capsules containing 25; 50 or 100 mg products; 1% solution in the ampoule and 5 ml (50 mg vials).
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