TRANEKSAMOVAYA ACID (Tranexamic acid).

     trans-4- (Aminometil) tsiklogeksankarbonovaya acid.

     Synonyms: Transamcha, Tsiklokapron, Tsiklo- F, Ekzatsil, Cyclokapron, Exacyl, Transamcha.

     The white crystalline powder. Soluble in water.

     Is competition plasminogen activator inhibitor.

     When you receive inside absorbed in part (40-50% dose), C max is 3 h, T? 2-h; return kidneys mostly unchanged.

     Apply in krovotecheniyah resulting from increasing fibrinoliza: haemophilia, haemorrhagic complications fibrinoliticheskoy therapy trombotsitopenicheskaya Purple, aplastic anemia, leukemia, bleeding during and after operations, delivery, lung, nasal, gastro intestinal bleeding, and meno- metrorragii and others.

     Assign inside and parenteral transmission.

     Inside appoint 0,25-0,5 g 2-4 times in the reactor during 3-15 days. The maximum daily dose of 2 grams.

     (Slow) intravenously or intramuscularly imposed on 0,25-0,5 g 1-2 times a day.

     Possible side effects: dizziness, weakness, drowsiness, tachycardia, arterial hypotension (with the rapid introduction of intravenous), a violation of color, skin allergic reactions.

     Contraindications: kidney failure, brain, heart attack miokarda, violation of color, pregnancy.

     Method of production: tablets of 0.25 g (N. 20, 100) and 0.5 g (N. 20); 10% solution for the reception inside the ampoule in 10 ml (1 g); 5% and 10% for solutions injections in the ampoule to 5 ml.

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