TOLMETIN (Tolmetin).

     Sodium salt metil-5- 1-(4-METHYLBENZOYL) -1 H nifrol-2- acetic acid.

     Synonym : Tolektin, Tolectin.

     The white crystalline powder. Mg in the water.

     Has antiinflammatory, blood analgesic and antipyretic effects.

     Quickly and completely absorbed, with max of 1-1,5 hour, T1 / 2 to 5 hours; Biotransformation are in the liver, kidneys available mostly in the form of metabolites.

      Applied and psoriaticheskom with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, rheumatoid arthritis vnesustavnom, frenzied state.

     Assign inside (after eating) for adults 0.4 g three times a day (up to 2 g / day) for children 15-20 mg / kg / day (3 admission).

     Possible side effects : allergic reactions, neuralgia, bronchospasm, peripheral oedema, disruption of the kidney and liver, DROWSINESS.

     The drug is not suitable for stomach ulcers and duodenal ulcer, ulcerative colitis, bronhoobstruktivnyh diseases violations of the liver and kidneys, heart failure, arterial hypertension.

     Anti enhance effects, antiagregantov, and the side effects of other NPVS, glucocorticosteroids, gold and drugs lithium alcohol; Diuretikov relaxed.

     Method of production : tablets of 0.2 and 0.6 g; Capsules of 0.4 g.

     Storage : List B.

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