Tirofiban (tirofiban)


TIROFIBAN (Tirofiban).
     N - (butilsulfaonil) -4-[4 - (4-pyridine) butoksi]? - Phenylalanine monogidrohlorid Monohydrate.
     Synonym : Agrastat, Aggrastate.
     Glikoproteinovyh receptor blockers ones IIb / IIIa platelet reversible action (receptor blockade lasts 4-6 h after Infusion compared with a 10 day abtsiksimaba).
     Molecule drug simulates tripeptidnuyu consistency in the structure fibrinogena, svyazyvayuschuyusya with the above menu.
     Applied (in combination with acetylsalicylic acid and unchanged) for the prevention of myocardial infarction in patients with unstable angina.
     Assign intravenous infuzionno initially at speeds of 0.4 µ g / kg per minute for 30 minutes, then 0.1 µ g / kg per minute for at least 48 h; The maximum duration of 108 hours Infusion
     Possible side effects are the same as those eptifibatida.
     Contraindications and precautions are the same as when applying abtsiksimaba.
     Product : 0,025% concentrate for infusion solutions in bottles of 50 ml.

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